PTH Antibody (D1.5) is a mouse monoclonal IgG1 provided at 100 µg/ml
raised against amino acids 53-84 of PTH of human origin
recommended for detection of PTH peptides (aa 53-68; 53-84; 7-84; and 1-84) of human, bovine and canine origin by WB, IP, IF and IHC(P); non cross-reactive with synthetic Parathyroid hormone peptides (aa 1-10; 1-34; 1-38)
See PTH/PTHrP-R (3D1.1): sc-12722 for PTH antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Parathyroid hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy. The gene encoding PTH-rP maps to human chromosome 12p12.1-p11.2. Both PTH and PTH-rP are regulated by vitamin D and steroid hormones, and both preferentially bind to specific PTH/PTH-rP receptors, then activate adenylate cyclase or PLC β via PKC activation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Thank you for your question. PTH has an expected molecular weight of approximately 9 kDa. If you have any questions, please contact our Technical Service Department and we would be happy to assist you.
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