Anti-PTH/PTHrP-R Antibody (3D1.1) is a mouse monoclonal IgG1 κ PTH/PTHrP-R antibody, cited in 31 publications, provided at 200 µg/ml
epitope mapping within amino acids 155-169 of PTH/PTHrP-R of human origin
Anti-PTH/PTHrP-R Antibody (3D1.1) is recommended for detection of PTH/PTHrP-R type I of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
Anti-PTH/PTHrP-R Antibody (3D1.1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to TRITC for IF, IHC(P) and FCM
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PTH/PTHrP-R (3D1.1): sc-12722.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PTH/PTHrP-R Antibody (3D1.1) for WB and IHC(P) applications. These reagents are now offered in bundles with PTH/PTHrP-R Antibody (3D1.1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PTH/PTHrP-R Antibody (3D1.1) is a high quality monoclonal PTH/PTHrP-R antibody (also designated Parathyroid Hormone 1 Receptor antibody, Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor antibody, Parathyroid Hormone Receptor 1 antibody, PTH/PTHrP Type I Receptor antibody, PTH/PTHr Receptor antibody, PTH1 Receptor antibody, PTHR1 antibody, PTHR antibody, Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor antibody, or Seven Transmembrane Helix Receptor antibody) suitable for the detection of the PTH/PTHrP-R protein of mouse, rat and human origin. PTH/PTHrP-R Antibody (3D1.1) is available as both the non-conjugated anti-PTH/PTHrP-R antibody form, as well as multiple conjugated forms of anti-PTH/PTHrP-R antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Parathyroid hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy. PTH and PTH-rP are both regulated by vitamin D and steroid hormones and preferentially bind to specific PTH/PTH-rP receptors, then activate adenylate cyclase or PLC β via PKC activation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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