PSMD1 Antibody (G-10): sc-514808

PSMD1 Antibody (G-10) is a mouse monoclonal IgG2b antibody that detects PSMD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSMD1, also known as S1 or p112, plays a crucial role as a regulatory component of the 26S proteasome, a vital protease complex responsible for the selective degradation of ubiquitinated proteins, which is essential for maintaining cellular homeostasis and regulating various cellular processes. PSMD1 is predominantly located in the nucleus and cytoplasm, where PSMD1 participates in the recognition and binding of substrates destined for degradation, thereby influencing protein turnover and cellular signaling pathways. PSMD1′s structural significance lies in being the largest of at least 11 non-ATPase regulatory subunits of the 19S regulatory lid, which is integral for the proper functioning of the proteasome. Anti-PSMD1 antibody (G-10) provides reliable detection and analysis of PSMD1, facilitating research into cellular regulation and potential implications in diseases associated with proteasome dysfunction.

The preferred PSMD1 antibody is PSMD1 Antibody (C-7): sc-166038.