PSMD1 Antibody (F-7): sc-166340

PSMD1 Antibody (F-7) is a mouse monoclonal IgG1 antibody that detects PSMD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSMD1, also known as S1 or p112, plays a crucial role as a regulatory component of the 26S proteasome, which is essential for the selective degradation of ubiquitinated proteins within eukaryotic cells. This process is vital for maintaining cellular homeostasis, regulating protein levels, and facilitating the removal of damaged or misfolded proteins, thereby preventing cellular stress and potential disease states. PSMD1 is predominantly expressed in skeletal muscle and heart tissues, highlighting its importance in muscle function and cardiac health. As the largest of at least 11 non-ATPase regulatory subunits of the 19S regulatory lid, PSMD1 is integral to substrate recognition and binding, ensuring that only appropriately tagged proteins are targeted for degradation. Anti-PSMD1 antibody (F-7) provides a reliable tool for researchers investigating the dynamics of protein turnover and the role of the proteasome in various biological processes and diseases.

The preferred PSMD1 antibody is PSMD1 Antibody (C-7): sc-166038.