Prostate Specific Antigen/AACT Complex Antibody (2F5): sc-53143

PSA/ACT Antibody (2F5) is a mouse monoclonal IgG1 antibody that detects prostate specific antigen (PSA) in human samples through applications such as western blotting (WB) and immunofluorescence (IF). PSA, also known as gamma-seminoprotein, seminin, p30 antigen, semenogelase, and kallikrein 3 (KLK3), is a serine protease primarily produced in the prostate gland, where PSA plays a crucial role in the liquefaction of semen by hydrolyzing semenogelin I, a major protein in seminal plasma. This enzymatic activity is vital for male fertility, as PSA allows sperm to swim freely after ejaculation. Elevated levels of PSA in the blood are often associated with prostate cancer, making PSA an important biomarker for early detection and monitoring of the disease. In addition to PSA presence in prostate tissues, PSA has also been found in accessory male sex glands and breast cancer tissues, highlighting PSA potential relevance in various malignancies. Anti-PSA/ACT antibody (2F5) is an essential tool for researchers studying prostate cancer and associated pathways, providing reliable detection and analysis of PSA in various experimental settings.

The preferred PSA/KLK3/Kallikrein 3/Prostate Specific Antigen antibody is PSA/KLK3/Kallikrein 3/Prostate Specific Antigen Antibody (A67-B/E3): sc-7316.