Prolactin Antibody (B-8): sc-271758
- Prolactin Antibody (B-8) is a mouse monoclonal IgG3 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 193-213 near the C-terminus of Prolactin of human origin
- recommended for detection of Prolactin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and porcine
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Prolactin Antibody (B-8) for WB applications. This reagent is now offered in a bundle with Prolactin Antibody (B-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Prolactin Antibody (B-8) is a mouse monoclonal IgG3 antibody that detects Prolactin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Prolactin, a 226 amino acid protein, is primarily secreted by the anterior pituitary gland and plays a crucial role in various physiological processes, including lactation, reproduction, and immune regulation. Prolactin (B-8) antibody is involved in the development of mammary tissue and has been implicated in mammary cancer, where Prolactin acts as both a mitogen and a differentiating agent, promoting cell proliferation and differentiation. Additionally, Prolactin enhances the proliferation of B cell hybridomas, significantly increasing antibody production, which is vital for effective immune responses. Prolactin′s ability to counteract the antiproliferative effects of the immunosuppressive cytokine TGF-beta further underscores its importance in maintaining immune homeostasis. Moreover, Prolactin′s association with autoimmune diseases such as arthritis and type 1 diabetes highlights its multifaceted role in health and disease, making anti-Prolactin antibody (B-8) an essential tool for researchers studying these critical biological processes.
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Prolactin Antibody (B-8) References:
- Decreased prolactin reserve in hemochromatosis. | Levy, CL. and Carlson, HE. 1978. J Clin Endocrinol Metab. 47: 444-6. PMID: 122405
- Prolactin, prolactin receptor and uncoupling proteins during fetal and neonatal development. | Pearce, S., et al. 2003. Proc Nutr Soc. 62: 421-7. PMID: 14506890
- Prolactin and prolactin receptor expression in cervical intraepithelial neoplasia and cancer. | Ascencio-Cedillo, R., et al. 2015. Pathol Oncol Res. 21: 241-6. PMID: 24990775
- ACTH and prolactin deficiency. | Puig, ML., et al. 1986. Acta Endocrinol (Copenh). 111: 296-9. PMID: 3008475
- Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. | Georgescu, T., et al. 2020. J Neuroendocrinol. 32: e12908. PMID: 33034148
- Prolactin, cortisol, and antidepressant treatment. | Fava, GA., et al. 1988. Am J Psychiatry. 145: 358-60. PMID: 3344852
- The comparative endocrinology of prolactin. | Bern, HA. and Nicoll, CS. 1968. Recent Prog Horm Res. 24: 681-720. PMID: 4882330
- Ectopic production of prolactin. | Turkington, RW. 1971. N Engl J Med. 285: 1455-8. PMID: 5166245
- Postpartum hostility and prolactin. | Mastrogiacomo, I., et al. Int J Psychiatry Med. 12: 289-94. PMID: 7166461
- Osteoporosis and prolactin. | Sheppeard, H. and Ward, DJ. 1980. Scand J Rheumatol. 9: 175-6. PMID: 7455627
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prolactin Antibody (B-8) | sc-271758 | 200 µg/ml | $322.00 | |||
Prolactin Antibody (B-8): m-IgGκ BP-HRP Bundle | sc-522051 | 200 µg Ab, 40 µg BP | $361.00 | |||
Prolactin (B-8) Neutralizing Peptide | sc-271758 P | 100 µg/0.5 ml | $69.00 |