Prolactin Antibody (A-7): sc-46698
- Prolactin Antibody (A-7) is a mouse monoclonal IgG1 κ Prolactin antibody, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 96-200 of Prolactin of human origin
- Prolactin Antibody (A-7) is recommended for detection of Prolactin of human origin by WB, IP, IF and ELISA
- Anti-Prolactin Antibody (A-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Prolactin Antibody (A-7) for WB applications. These reagents are now offered in bundles with Prolactin Antibody (A-7) (see ordering information below).
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Prolactin Antibody (A-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Prolactin protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Prolactin antibody (A-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Prolactin, a 226 amino acid protein, is primarily secreted by the anterior pituitary gland and plays a crucial role in numerous physiological processes, including cell growth, reproduction, and immune regulation. Notably, Prolactin is secreted by endothelial cells during angiogenesis and has been implicated in mammary cancer development, acting as both a mitogen and a differentiating agent. Prolactin enhances B cell hybridoma proliferation, significantly contributing to increased antibody production and immune responses. Additionally, Prolactin counteracts the antiproliferative effects of immunosuppressive cytokine TGF-beta, linking Prolactin to various autoimmune diseases such as arthritis and type 1 diabetes. With diverse roles in health and disease, Prolactin continues to be a vital target for research and therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Prolactin Antibody (A-7) References:
- Prolactin and autoimmunity. | Jara, LJ., et al. 2011. Clin Rev Allergy Immunol. 40: 50-9. PMID: 19911311
- Prolactin and adipose tissue. | Carré, N. and Binart, N. 2014. Biochimie. 97: 16-21. PMID: 24120689
- Prolactin in inflammatory response. | Pereira Suarez, AL., et al. 2015. Adv Exp Med Biol. 846: 243-64. PMID: 25472542
- Prolactin and Autoimmunity. | Borba, VV., et al. 2018. Front Immunol. 9: 73. PMID: 29483903
- Prolactin system in the hippocampus. | Carretero, J., et al. 2019. Cell Tissue Res. 375: 193-199. PMID: 29806058
- Prolactin and alteration of fertility. | Štelcl, M., et al. 2018. Ceska Gynekol. 83: 232-235. PMID: 30764625
- Prolactin Elevations and Permeability Glycoprotein. | El-Mallakh, RS. and Watkins, J. 2019. Prim Care Companion CNS Disord. 21: PMID: 31106995
- Metabolic effects of prolactin. | Pirchio, R., et al. 2022. Front Endocrinol (Lausanne). 13: 1015520. PMID: 36237192
- Prolactin and pain of endometriosis. | Lee, GJ., et al. 2023. Pharmacol Ther. 247: 108435. PMID: 37169264
- Prolactin and breast cancer. | Kleinberg, DL. 1987. N Engl J Med. 316: 269-71. PMID: 3796703
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prolactin Antibody (A-7) | sc-46698 | 200 µg/ml | $322.00 | |||
Prolactin Antibody (A-7): m-IgG Fc BP-HRP Bundle | sc-526728 | 200 µg Ab; 10 µg BP | $361.00 | |||
Prolactin Antibody (A-7): m-IgG1 BP-HRP Bundle | sc-532101 | 200 µg Ab; 20 µg BP | $361.00 | |||
Prolactin Antibody (A-7) AC | sc-46698 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Prolactin Antibody (A-7) HRP | sc-46698 HRP | 200 µg/ml | $322.00 | |||
Prolactin Antibody (A-7) FITC | sc-46698 FITC | 200 µg/ml | $336.00 | |||
Prolactin Antibody (A-7) PE | sc-46698 PE | 200 µg/ml | $349.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 488 | sc-46698 AF488 | 200 µg/ml | $364.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 546 | sc-46698 AF546 | 200 µg/ml | $364.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 594 | sc-46698 AF594 | 200 µg/ml | $364.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 647 | sc-46698 AF647 | 200 µg/ml | $364.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 680 | sc-46698 AF680 | 200 µg/ml | $364.00 | |||
Prolactin Antibody (A-7) Alexa Fluor® 790 | sc-46698 AF790 | 200 µg/ml | $364.00 |