PP1β Antibody (A-6): sc-365678
- PP1β Antibody (A-6) is a mouse monoclonal IgG2b κ PP1β antibody, cited in 11 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 295-322 at the C-terminus of PP1β of human origin
- PP1 beta Antibody (A-6) is recommended for detection of PP1β of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
- Anti-PP1 beta Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP1β Antibody (A-6) for WB applications. These reagents are now offered in bundles with PP1β Antibody (A-6) (see ordering information below).
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PP1β Antibody (A-6) is a mouse monoclonal IgG2b kappa light chain antibody designed to target an epitope spanning amino acids 295-322 at the C-terminus of human Protein Phosphatase 1 Beta (PP1β), also known as PPP1CB. PP1β is a critical catalytic subunit of the Protein Phosphatase 1 (PP1) family, featuring a conserved catalytic domain responsible for serine/threonine phosphatase activity and a C-terminal region essential for interactions with regulatory and targeting proteins. The structural integrity of PP1β, particularly at the C-terminus, is pivotal for precise localization within both nucleus and cytoplasm of eukaryotic cells, enabling regulation of key cellular processes such as cell division, metabolism, and apoptosis through targeted dephosphorylation of specific substrates. Anti-PP1β antibody (A-6) demonstrates broad species reactivity, effectively recognizing PP1β proteins from mouse, rat, human, canine, bovine, porcine, and avian origins, making PP1β monoclonal antibody (A-6) versatile for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Available in both non-conjugated form and various conjugated forms such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, PP1β (A-6) antibody provides researchers with flexible options to meet diverse experimental needs. Anti-PP1β antibody (A-6) enables investigation of structural conformation and interaction dynamics of PP1β, offering deeper insights into cellular signaling networks and implications in both physiological and pathological contexts. Understanding PP1β structure and function is crucial for elucidating impact on cellular processes and potential therapeutic targeting in diseases characterized by dysregulated phosphatase activity, making PP1β (A-6) monoclonal antibody an indispensable research tool.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP1β Antibody (A-6) | sc-365678 | 200 µg/ml | $322.00 | |||
PP1β Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-529436 | 200 µg Ab; 10 µg BP | $361.00 | |||
PP1β Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-522324 | 200 µg Ab, 40 µg BP | $361.00 | |||
PP1β Antibody (A-6): m-IgG2b BP-HRP Bundle | sc-550110 | 200 µg Ab; 10 µg BP | $361.00 | |||
PP1β Antibody (A-6) AC | sc-365678 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PP1β Antibody (A-6) HRP | sc-365678 HRP | 200 µg/ml | $322.00 | |||
PP1β Antibody (A-6) FITC | sc-365678 FITC | 200 µg/ml | $336.00 | |||
PP1β Antibody (A-6) PE | sc-365678 PE | 200 µg/ml | $349.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 488 | sc-365678 AF488 | 200 µg/ml | $364.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 546 | sc-365678 AF546 | 200 µg/ml | $364.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 594 | sc-365678 AF594 | 200 µg/ml | $364.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 647 | sc-365678 AF647 | 200 µg/ml | $364.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 680 | sc-365678 AF680 | 200 µg/ml | $364.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 790 | sc-365678 AF790 | 200 µg/ml | $364.00 | |||
PP1β (A-6) Neutralizing Peptide | sc-365678 P | 100 µg/0.5 ml | $69.00 |