Plk Antibody (E-2): sc-55504
- Plk Antibody (E-2) is a mouse monoclonal IgG2a κ, cited in 13 publications, provided at 200 µg/ml
- raised against amino acids 261-412 mapping within an internal region of Plk of human origin
- recommended for detection of Plk of mouse, rat and human origin by WB, IP, IF and ELISA
- See Plk (F-8): sc-17783 for Plk antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Plk Antibody (E-2) for WB applications. These reagents are now offered in bundles with Plk Antibody (E-2) (see ordering information below).
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SEE ALSO...
Plk Antibody (E-2) is a mouse monoclonal IgG2a antibody that detects Plk in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Plk antibody (E-2) plays a crucial role in cell cycle regulation, as Plk is a serine/threonine kinase essential for proper functioning of the mitotic spindle, which is vital for accurate chromosome segregation during cell division. Plk accumulates during the S and G2 phases of the cell cycle, with levels and catalytic activity peaking at the onset of mitosis, highlighting its importance in facilitating the transition into this critical phase. Following mitosis, Plk levels rapidly decrease, indicating a tightly regulated expression pattern. Notably, Plk is expressed in mitotically active tissues such as the colon and placenta, as well as in various tumors, suggesting potential as a biomarker for cell proliferation and a target for cancer therapies. Plk (E-2) antibody′s ability to effectively detect Plk across multiple species makes this reagent an invaluable tool for researchers studying cell cycle dynamics and cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Plk Antibody (E-2) | sc-55504 | 200 µg/ml | $322.00 | |||
Plk Antibody (E-2): m-IgG Fc BP-HRP Bundle | sc-537056 | 200 µg Ab; 10 µg BP | $361.00 | |||
Plk Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-534241 | 200 µg Ab; 40 µg BP | $361.00 | |||
Plk Antibody (E-2): m-IgG2a BP-HRP Bundle | sc-547926 | 200 µg Ab; 10 µg BP | $361.00 |