PKC omega Antibody (B-7): sc-393218

PKC ζ Antibody (H-1) is a mouse monoclonal IgG2a antibody that targets an epitope mapping between amino acids 573-592 at the C-terminus of rat-origin Protein Kinase C zeta (PKC ζ), also known as PRKCZ. Anti-PKC ζ antibody (H-1) reacts with mouse, rat, and human species and is suitable for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PKC ζ is an atypical member of the protein kinase C family, playing a crucial role in various cellular processes such as cell growth, differentiation, survival, gene expression, and membrane function. Unlike conventional PKCs, PKC ζ activation is independent of calcium and diacylglycerol (DAG), allowing unique function within signaling pathways. PKC ζ is involved in the regulation of NF-κB activation, insulin signaling, cell polarity, and the PI3K/Akt pathway, making PKC ζ significant in understanding diseases like diabetes, cancer, and immune disorders. PKC ζ′s involvement in cell survival and proliferation underscores importance as a potential therapeutic target. Additionally, distinct activation mechanisms make PKC ζ an intriguing subject in signal transduction research, potentially revealing new insights into cellular communication pathways. Using PKC ζ monoclonal antibody (H-1), researchers can effectively study PKC ζ expression and function in various biological contexts, aiding in the development of novel treatments.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-PKC omega Antibody (B-7) has 6 citations in a variety of scientific publications.

Primary antibodies like Anti-PKC omega Antibody (B-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

PKC omega Antibody (B-7) Specifications

Alternate Product Name: PKC zeta

Product Clone Name: B-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 309-592

Epitope Target: PKC ζ

Epitope Species: human

Product Reactivity/Detection: PKC ζ

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 6 citations in various scientific publications

Available Conjugates/Forms for PKC omega Antibody (B-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred PKC zeta antibody is PKC zeta Antibody (H-1): sc-17781.