Anti-PKC α Antibody (H-7) is a mouse monoclonal IgG1 κ PKC α antibody, cited in 268 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 651-672 at the C-terminus of PKC α of human origin
Anti-PKC alpha Antibody (H-7) is recommended for detection of PKC α of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-PKC alpha Antibody (H-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PKC α (H-7): sc-8393.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PKC α Antibody (H-7) for WB and IHC(P) applications. These reagents are now offered in bundles with PKC α Antibody (H-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PKC α Antibody (H-7) is a high quality monoclonal PKC alpha antibody (also designated PRKCA antibody) suitable for the detection of the PKC alpha protein of mouse, rat and human origin. PKC α Antibody (H-7) is available as both the non-conjugated anti-PKC alpha antibody form, as well as multiple conjugated forms of anti-PKC alpha antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor-promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, ζ, η, θ, λ/ι, µ and ν). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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