phostensin Antibody (F-5): sc-365099

Phostensin Antibody (F-5) is a mouse monoclonal IgG2a antibody that detects phostensin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Phostensin, also known as KIAA1949, is a 613 amino acid protein that plays a crucial role in cellular regulation by acting as a regulatory subunit that targets protein phosphatase 1 (PP1) to F-Actin within the cytoskeleton. This targeting is vital for proper functioning of various cellular processes, including cell division and apoptosis, as PP1 can effectively dephosphorylate substrates, thereby modulating their activity. Phostensin presence in key tissues such as spleen, ovary, lung, and liver highlights phostensin importance in maintaining cellular homeostasis and responding to physiological changes. Additionally, phostensin exists in two isoforms due to alternative splicing, which may allow for functional diversity and adaptability in regulatory roles. Anti-phostensin antibody (F-5) is an essential tool for researchers studying intricate mechanisms of cellular signaling and regulation.

The preferred phostensin antibody is phostensin Antibody (H-9): sc-376816.