PHF13 Antibody (G-9): sc-376086
- PHF13 Antibody (G-9) is a mouse monoclonal IgG2a κ PHF13 antibody provided at 200 µg/ml
- raised against amino acids 126-220 mapping within an internal region of PHF13 of human origin
- PHF13 Antibody (G-9) is recommended for detection of PHF13 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PHF13 Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PHF13 Antibody (G-9) for WB and IHC(P) applications. These reagents are now offered in bundles with PHF13 Antibody (G-9) (see ordering information below).
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PHF13 Antibody (G-9) is a mouse monoclonal IgG2a kappa light chain antibody that detects PHF13 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PHF13 (G-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PHF13, also known as PHD finger protein 13 or SPOC1, is a 300 amino acid protein characterized by the presence of a PHD-type zinc finger, which plays a crucial role in transcriptional regulation. PHF13 is primarily located in the nucleus, where PHF13 is involved in the regulation of gene expression, making PHF13 essential for various cellular processes, including differentiation and response to environmental signals. The gene encoding PHF13 is situated on human chromosome 1, a region spanning 260 million base pairs and containing over 3,000 genes, with significant association to numerous diseases, including familial adenomatous polyposis, Stickler syndrome, and various cancers. Aberrations in chromosome 1 have been linked to head and neck cancer, malignant melanoma, and multiple myeloma, highlighting PHF13′s importance in both normal cellular function and disease pathology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PHF13 Antibody (G-9) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- SPOC1, a novel PHD-finger protein: association with residual disease and survival in ovarian cancer. | Mohrmann, G., et al. 2005. Int J Cancer. 116: 547-54. PMID: 15825179
- Cell biology: ageing nucleus gets out of shape. | Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PHF13 Antibody (G-9) | sc-376086 | 200 µg/ml | $322.00 | |||
PHF13 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-525993 | 200 µg Ab; 10 µg BP | $361.00 | |||
PHF13 Antibody (G-9): m-IgG2a BP-HRP Bundle | sc-546479 | 200 µg Ab; 10 µg BP | $361.00 | |||
PHF13 Antibody (G-9) AC | sc-376086 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PHF13 Antibody (G-9) HRP | sc-376086 HRP | 200 µg/ml | $322.00 | |||
PHF13 Antibody (G-9) FITC | sc-376086 FITC | 200 µg/ml | $336.00 | |||
PHF13 Antibody (G-9) PE | sc-376086 PE | 200 µg/ml | $349.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 488 | sc-376086 AF488 | 200 µg/ml | $364.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 546 | sc-376086 AF546 | 200 µg/ml | $364.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 594 | sc-376086 AF594 | 200 µg/ml | $364.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 647 | sc-376086 AF647 | 200 µg/ml | $364.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 680 | sc-376086 AF680 | 200 µg/ml | $364.00 | |||
PHF13 Antibody (G-9) Alexa Fluor® 790 | sc-376086 AF790 | 200 µg/ml | $364.00 |