Peroxin 26 Antibody (F-7): sc-393884
- Peroxin 26 Antibody (F-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 3-180 mapping near the N-terminus of Peroxin 26 of human origin
- recommended for detection of Peroxin 26 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Peroxin 26 Antibody (F-7) for WB applications. These reagents are now offered in bundles with Peroxin 26 Antibody (F-7) (see ordering information below).
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Peroxin 26 Antibody (F-7) is a mouse monoclonal IgG1 antibody that detects Peroxin 26 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Peroxin 26, also known as PEX26, plays a crucial role in peroxisome biogenesis by facilitating the recruitment, shuttling, and anchoring of Peroxin 1 and Peroxin 6 to the peroxisome membrane, which is essential for the formation of heteromeric AAA ATPase complexes. These complexes are vital for the import of various proteins, including catalase, into peroxisomes, thereby ensuring the proper functioning of these organelles. Defects in the gene encoding Peroxin 26 can lead to severe peroxisome-related disorders such as Zellweger syndrome, infantile Refsum disease, and peroxisome biogenesis disorder complementation group 8. Using anti-Peroxin 26 antibody (F-7) in research can provide insights into peroxisome function mechanisms and their dysfunction′s impact on human health.
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Peroxin 26 Antibody (F-7) References:
- The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes. | Matsumoto, N., et al. 2003. Nat Cell Biol. 5: 454-60. PMID: 12717447
- Mutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlation. | Matsumoto, N., et al. 2003. Am J Hum Genet. 73: 233-46. PMID: 12851857
- Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway. | Yagita, Y., et al. 2013. J Cell Biol. 200: 651-66. PMID: 23460677
- Next-generation sequencing reveals the mutational landscape of clinically diagnosed Usher syndrome: copy number variations, phenocopies, a predominant target for translational read-through, and PEX26 mutated in Heimler syndrome. | Neuhaus, C., et al. 2017. Mol Genet Genomic Med. 5: 531-552. PMID: 28944237
- A novel mutation in the PEX26 gene in a family from Dagestan with members affected by Zellweger spectrum disorder. | Semenova, NA., et al. 2021. Mol Genet Metab Rep. 27: 100754. PMID: 33912394
- Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance. | Dahabieh, MS., et al. 2022. Autophagy. 18: 540-558. PMID: 34074205
- PEX26 gene genotype-phenotype correlation in neonates with Zellweger syndrome. | He, Y., et al. 2021. Transl Pediatr. 10: 1825-1833. PMID: 34430430
- Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency. | Lotz-Havla, AS., et al. 2021. Front Genet. 12: 726174. PMID: 34804114
- PEX26 Functions as a Metastasis Suppressor in Colorectal Cancer. | Yan, B., et al. 2024. Dig Dis Sci. 69: 112-122. PMID: 37957408
- Identification of a novel heterozygous variant in the PEX26 gene in an infant: a case report. | Huang, Y., et al. 2024. Transl Pediatr. 13: 192-199. PMID: 38323187
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Peroxin 26 Antibody (F-7) | sc-393884 | 200 µg/ml | $322.00 | |||
Peroxin 26 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-538330 | 200 µg Ab; 10 µg BP | $361.00 | |||
Peroxin 26 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-535917 | 200 µg Ab; 40 µg BP | $361.00 | |||
Peroxin 26 Antibody (F-7): m-IgG1 BP-HRP Bundle | sc-545646 | 200 µg Ab; 20 µg BP | $361.00 |