Peroxin 13 Antibody (D-5): sc-271477
- Peroxin 13 Antibody (D-5) is a mouse monoclonal IgG2b κ Peroxin 13 antibody, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 254-403 mapping at the C-terminus of Peroxin 13 of human origin
- Peroxin 13 Antibody (D-5) is recommended for detection of Peroxin 13 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Peroxin 13 Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Peroxin 13 Antibody (D-5) for WB applications. These reagents are now offered in bundles with Peroxin 13 Antibody (D-5) (see ordering information below).
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Peroxin 13 Antibody (D-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects Peroxin 13 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Peroxin 13 (D-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Peroxin 13 protein plays a crucial role in peroxisome biogenesis, which is essential for cellular metabolism and maintenance of cellular homeostasis. Peroxisomes are single-membrane-bound organelles that participate in various metabolic pathways, including breakdown of very long-chain fatty acids and detoxification of hydrogen peroxide. Proper functioning of Peroxin 13 is vital as Peroxin 13 interacts with other peroxins, such as Peroxin 5 and Peroxin 7, to facilitate import of proteins into peroxisomes, ensuring these organelles can perform metabolic functions effectively. Dysregulation or dysfunction of Peroxin 13 has been linked to peroxisome biogenesis disorders, highlighting Peroxin 13′s importance in human health. With proven detection of Peroxin 13 across multiple species and applications, anti-Peroxin 13 antibody (D-5) serves as an invaluable tool for researchers studying peroxisome-related processes and disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Peroxin 13 Antibody (D-5) References:
- Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes. | Girzalsky, W., et al. 1999. J Cell Biol. 144: 1151-62. PMID: 10087260
- Peroxisome biogenesis and peroxisome biogenesis disorders. | Fujiki, Y. 2000. FEBS Lett. 476: 42-6. PMID: 10878247
- The peroxisome biogenesis factors pex4p, pex22p, pex1p, and pex6p act in the terminal steps of peroxisomal matrix protein import. | Collins, CS., et al. 2000. Mol Cell Biol. 20: 7516-26. PMID: 11003648
- The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction. | Barnett, P., et al. 2000. EMBO J. 19: 6382-91. PMID: 11101511
- Organelle disease: peroxisomal disorders. | Gärtner, J. 2000. Eur J Pediatr. 159 Suppl 3: S236-9. PMID: 11216907
- Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p. | Dodt, G., et al. 2001. J Biol Chem. 276: 41769-81. PMID: 11546814
- Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes. | Björkman, J., et al. 2002. Genomics. 79: 162-8. PMID: 11829486
- Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import. | Otera, H., et al. 2002. Mol Cell Biol. 22: 1639-55. PMID: 11865044
- Cellular and molecular aspects of Zellweger syndrome and other peroxisome biogenesis disorders. | Brosius, U. and Gärtner, J. 2002. Cell Mol Life Sci. 59: 1058-69. PMID: 12169017
- Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene. | Björkman, J., et al. 1998. Genomics. 54: 521-8. PMID: 9878256
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Peroxin 13 Antibody (D-5) | sc-271477 | 200 µg/ml | $322.00 | |||
Peroxin 13 Antibody (D-5): m-IgGκ BP-HRP Bundle | sc-521954 | 200 µg Ab, 40 µg BP | $361.00 | |||
Peroxin 13 Antibody (D-5): m-IgG2b BP-HRP Bundle | sc-548988 | 200 µg Ab; 10 µg BP | $361.00 | |||
Peroxin 13 Antibody (D-5) AC | sc-271477 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Peroxin 13 Antibody (D-5) HRP | sc-271477 HRP | 200 µg/ml | $322.00 | |||
Peroxin 13 Antibody (D-5) FITC | sc-271477 FITC | 200 µg/ml | $336.00 | |||
Peroxin 13 Antibody (D-5) PE | sc-271477 PE | 200 µg/ml | $349.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 488 | sc-271477 AF488 | 200 µg/ml | $364.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 546 | sc-271477 AF546 | 200 µg/ml | $364.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 594 | sc-271477 AF594 | 200 µg/ml | $364.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 647 | sc-271477 AF647 | 200 µg/ml | $364.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 680 | sc-271477 AF680 | 200 µg/ml | $364.00 | |||
Peroxin 13 Antibody (D-5) Alexa Fluor® 790 | sc-271477 AF790 | 200 µg/ml | $364.00 |