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Per1 Antibody (2715C2) is a mouse monoclonal IgG1 antibody that detects Per1 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Per1 plays a crucial role in the regulation of circadian rhythms, acting as a key component of the molecular clock within the suprachiasmatic nucleus (SCN) of the brain. Per1 is essential for maintaining the timing of various physiological processes, including hormonal rhythms and sleep-wake cycles, which are vital for overall health and well-being. Per1 exhibits distinct isoforms that are compartmentalized within the cell; the full-length isoform is predominantly located in the cytoplasm, while a shorter nuclear isoform is also present. This compartmentalization suggests that Per1 may have different functional roles depending on its location, influencing the transcriptional regulation of other clock genes and thereby impacting the overall circadian rhythm. The interaction of Per1 with other proteins, such as Tim, further underscores its importance in the intricate network of circadian regulation, as these interactions can modulate the activity of the Clock-BMAL1 complex, which is critical for the transcription of circadian genes. With specificity for human samples and proven applications, anti-Per1 antibody (2715C2) is an invaluable tool for researchers studying the molecular mechanisms underlying circadian biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Per1 Antibody (2715C2) | sc-81574 | 100 µg/ml | $339.00 |