CD31/PECAM-1 Antibody (E-8): sc-133091
- CD31/PECAM-1 Antibody (E-8) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 28-327 mapping at the N-terminus of PECAM-1 of human origin
- recommended for detection of PECAM-1 of human origin by WB, IP, IF, IHC(P) and ELISA
- See CD31/PECAM-1 (H-3): sc-376764 for CD31/PECAM-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD31/PECAM-1 Antibody (E-8) for WB and IHC(P) applications. These reagents are now offered in bundles with CD31/PECAM-1 Antibody (E-8) (see ordering information below).
QUICK LINKS
PECAM-1 Antibody (E-8) is a mouse monoclonal IgG1 antibody that detects PECAM-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PECAM-1, also known as CD31, is a crucial glycoprotein primarily located on the surfaces of endothelial cells, platelets, and certain leukocytes, playing a vital role in mediating cell-cell adhesion and transendothelial migration. PECAM-1 is essential for maintaining vascular integrity and regulating inflammatory responses, as PECAM-1 facilitates the movement of immune cells across the endothelium during immune surveillance and tissue repair. Additionally, PECAM-1 is involved in angiogenesis, the process of new blood vessel formation, which is critical for tumor growth and metastasis. The expression of PECAM-1 is often upregulated in various pathological conditions, including cancer, making PECAM-1 a significant marker for studying tumor biology and the immune response. Anti-PECAM-1 antibody (E-8) provides a reliable tool for researchers investigating these processes, enabling a deeper understanding of the molecular mechanisms underlying vascular biology and immune interactions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (E-8) | sc-133091 | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-537341 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD31/PECAM-1 Antibody (E-8): m-IgGκ BP-HRP Bundle | sc-534583 | 200 µg Ab; 40 µg BP | $354.00 | |||
CD31/PECAM-1 Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-545145 | 200 µg Ab; 20 µg BP | $354.00 |