CD31/PECAM-1 Antibody (D-11): sc-46694

PECAM-1 Antibody (D-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects PECAM-1 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-PECAM-1 antibody (D-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PECAM-1, also known as CD31, is a crucial glycoprotein primarily located on the surfaces of endothelial cells, platelets, and certain immune cells, playing a vital role in mediating cell-cell adhesion and transendothelial migration. PECAM-1 maintains vascular integrity and facilitates leukocyte trafficking during inflammatory responses, which is particularly important in processes such as wound healing and immune surveillance. PECAM-1′s interaction with other adhesion molecules, such as integrins, underscores its significance in both normal physiological functions and pathological conditions, including cancer metastasis and cardiovascular diseases. PECAM-1 monoclonal antibody (D-11) helps researchers gain valuable insights into the mechanisms of cell adhesion and migration, contributing to a better understanding of various diseases and potential therapeutic targets.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD31/PECAM-1 Antibody (D-11) has 19 citations in a variety of scientific publications.

Primary antibodies like Anti-CD31/PECAM-1 Antibody (D-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD31/PECAM-1 Antibody (D-11) Specifications

Alternate Product Name: CD31

Product Clone Name: D-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 376-560

Epitope Target: PECAM-1

Epitope Species: mouse

Product Reactivity/Detection: PECAM-1

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 19 citations in various scientific publications

Available Conjugates/Forms for CD31/PECAM-1 Antibody (D-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred CD31/PECAM-1 antibody is CD31/PECAM-1 Antibody (MEC 13.3): sc-18916.