PDZK1 Antibody (H-1): sc-390932
- PDZK1 Antibody (H-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 419-446 near the C-terminus of PDZK1 of mouse origin
- recommended for detection of PDZK1 of mouse and rat origin and Diphor-1 of rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PDZK1 Antibody (H-1) for WB applications. These reagents are now offered in bundles with PDZK1 Antibody (H-1) (see ordering information below).
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PDZK1 Antibody (H-1) is a mouse monoclonal IgG1 antibody that detects PDZK1 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PDZK1, also known as Diphor-1 in rats, is a crucial protein containing four PDZ domains, which are essential for organizing various ion channels and receptors at the plasma membrane of epithelial cells. This localization allows PDZK1 to facilitate interactions between multiple types of channels, playing a vital role in signal transduction and cellular communication. PDZK1′s function as an adaptor between different cell surface receptors is particularly important in maintaining cellular homeostasis and regulating ion transport. PDZK1 has been found to be markedly upregulated in human carcinomas of epithelial origin, suggesting involvement in cancer progression and potential contribution to multidrug resistance through interactions with proteins like MAP17 and cMOAT. Anti-PDZK1 antibody (H-1) serves as a valuable tool for researchers investigating cancer resistance mechanisms to chemotherapeutic agents and broader implications of PDZ domain-containing proteins in cellular signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDZK1 Antibody (H-1) | sc-390932 | 200 µg/ml | $322.00 | |||
PDZK1 Antibody (H-1): m-IgG Fc BP-HRP Bundle | sc-540871 | 200 µg Ab; 10 µg BP | $361.00 | |||
PDZK1 Antibody (H-1): m-IgG1 BP-HRP Bundle | sc-542431 | 200 µg Ab; 20 µg BP | $361.00 | |||
PDZK1 (H-1) Neutralizing Peptide | sc-390932 P | 100 µg/0.5 ml | $69.00 |