PCNP Antibody (2707C2a): sc-130635
- PCNP Antibody (2707C2a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the C-terminus of PCNP of human origin
- recommended for detection of PCNP of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PCNP Antibody (2707C2a). This work is in progress.
QUICK LINKS
SEE ALSO...
PCNP Antibody (2707C2a) is a mouse monoclonal IgG1 antibody that detects PEST proteolytic signal containing nuclear protein (PCNP) in human samples through western blotting (WB) and immunoprecipitation (IP) applications. PCNP is a crucial 178 amino acid nuclear protein that plays a significant role in cell cycle regulation and tumorigenesis, making PCNP an important target for cancer research. PCNP (2707C2a) antibody recognizes a protein primarily located in the nucleus, where PCNP is involved in the regulation of gene expression and the maintenance of genomic stability. Nuclear localization allows PCNP to interact with various transcription factors and other nuclear proteins, thereby influencing cellular processes such as proliferation and apoptosis. PCNP undergoes post-translational modifications, including ubiquitination by the NIRF ubiquitin ligase, which can affect stability and function. The gene encoding PCNP is situated on human chromosome 3q12.3, a region associated with several key tumor suppressor genes and genetic diseases, underscoring PCNP′s relevance in both normal cellular function and disease pathology. With insights into the mechanisms of tumorigenesis, anti-PCNP antibody (2707C2a) serves as an essential tool for researchers investigating cancer biology and therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PCNP Antibody (2707C2a) | sc-130635 | 100 µg/ml | $333.00 |