PCDH21 Antibody (E-8): sc-514764
- PCDH21 Antibody (E-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 329-527 mapping within an internal region of PCDH21 of human origin
- recommended for detection of PCDH21 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PCDH21 Antibody (E-8) for WB applications. These reagents are now offered in bundles with PCDH21 Antibody (E-8) (see ordering information below).
PCDH21 Antibody (E-8) is a mouse monoclonal IgG1 antibody that detects protocadherin 21 (PCDH21) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PCDH21 is an 859 amino acid single-pass membrane protein that plays a crucial role in the outer segments of photoreceptor cells, where PCDH21 is essential for maintaining structural integrity. PCDH21 contains six cadherin domains and exists in multiple alternatively spliced isoforms, highlighting PCDH21′s versatility in cellular functions. As a calcium-dependent cell adhesion protein, PCDH21 is vital for establishing and maintaining neuronal connections, particularly in the retina, where PCDH21 contributes to synaptic network formation. Proper functioning of PCDH21 is important not only for visual signal transduction but also for overall neuronal health, as disruptions in PCDH21 expression or function can lead to retinal degeneration and other neurological disorders. Anti-PCDH21 antibody (E-8) is an invaluable tool for researchers studying cell adhesion and neuronal connectivity dynamics in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PCDH21 Antibody (E-8) | sc-514764 | 200 µg/ml | $316.00 | |||
PCDH21 Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-538697 | 200 µg Ab; 10 µg BP | $354.00 | |||
PCDH21 Antibody (E-8): m-IgGκ BP-HRP Bundle | sc-536359 | 200 µg Ab; 40 µg BP | $354.00 | |||
PCDH21 Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-545839 | 200 µg Ab; 20 µg BP | $354.00 |