PBGD Antibody (B-3): sc-166742
- PBGD Antibody (B-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 62-361 mapping at the C-terminus of PBGD of human origin
- recommended for detection of PBGD of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PBGD Antibody (B-3) for WB applications. These reagents are now offered in bundles with PBGD Antibody (B-3) (see ordering information below).
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SEE ALSO...
PBGD Antibody (B-3) is a mouse monoclonal IgG1 antibody that detects porphobilinogen deaminase (PBGD) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PBGD plays a crucial role in the heme synthesis pathway, catalyzing the conversion of porphobilinogen into hydroxymethylbilane, which is a key intermediate in the production of heme, an essential component of hemoglobin and various enzymes. The proper functioning of PBGD is vital, as deficiencies in this enzyme can lead to acute intermittent porphyria (AIP), a serious inherited disorder characterized by neurological dysfunctions, abdominal pain, and elevated levels of porphobilinogen and aminolevulinic acid in the urine. Understanding the structure and function of PBGD is important not only for diagnosing and managing AIP but also for exploring potential therapeutic interventions that could mitigate the effects of this disorder. Anti-PBGD antibody (B-3) is an invaluable tool for researchers studying the complexities of heme metabolism and its implications in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PBGD Antibody (B-3) | sc-166742 | 200 µg/ml | $322.00 | |||
PBGD Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-540149 | 200 µg Ab; 10 µg BP | $361.00 | |||
PBGD Antibody (B-3): m-IgG1 BP-HRP Bundle | sc-541935 | 200 µg Ab; 20 µg BP | $361.00 |