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Pancreatic Lipase Antibody (G-11): sc-393158

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Datasheets
  • Pancreatic Lipase Antibody (G-11) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 29-47 near the N-terminus of Pancreatic Lipase of rat origin
  • recommended for detection of Pancreatic Lipase of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Pancreatic Lipase Antibody (G-11) for WB applications. These reagents are now offered in bundles with Pancreatic Lipase Antibody (G-11) (see ordering information below).
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    Pancreatic Lipase Antibody (G-11) is a mouse monoclonal IgG2a antibody that detects pancreatic lipase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Pancreatic lipase is a critical enzyme in the digestive system, primarily located in the pancreas, where anti-pancreatic lipase antibody (G-11) plays a vital role in the breakdown of dietary fats. By hydrolyzing triglycerides into diglycerides, monoglycerides, and free fatty acids, pancreatic lipase facilitates the absorption of lipids in the intestines, making pancreatic lipase (G-11) monoclonal antibody essential for proper nutrient utilization and energy production. Dysregulation of pancreatic lipase activity can lead to various metabolic disorders, highlighting pancreatic lipase antibody (G-11)′s importance in maintaining lipid homeostasis. Anti-pancreatic lipase antibody (G-11) is an invaluable tool for researchers studying lipid metabolism and related diseases, providing reliable detection and analysis of this key enzyme in various biological contexts.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Pancreatic Lipase Antibody (G-11) References:

    1. Kinetic behavior of the pancreatic lipase-colipase-lipid system.  |  Brockman, HL. 2000. Biochimie. 82: 987-95. PMID: 11099795
    2. Pancreatic lipase-related protein 2 is the major colipase-dependent pancreatic lipase in suckling mice.  |  D'Agostino, D. and Lowe, ME. 2004. J Nutr. 134: 132-4. PMID: 14704305
    3. Physiological parameters governing the action of pancreatic lipase.  |  Brownlee, IA., et al. 2010. Nutr Res Rev. 23: 146-54. PMID: 20193096
    4. Pancreatic lipase inhibitory activity of phlorotannins isolated from Eisenia bicyclis.  |  Eom, SH., et al. 2013. Phytother Res. 27: 148-51. PMID: 22473750
    5. Pancreatic lipase-colipase binds strongly to the thylakoid membrane surface.  |  Emek, SC., et al. 2013. J Sci Food Agric. 93: 2254-8. PMID: 23355304
    6. Daisaikoto Inhibits Pancreatic Lipase Activity and Decreases Serum Triglyceride Levels in Mice.  |  Matsuo, Y., et al. 2018. Biol Pharm Bull. 41: 1485-1488. PMID: 30175784
    7. Gallotannins are uncompetitive inhibitors of pancreatic lipase activity.  |  Moreno-Córdova, EN., et al. 2020. Biophys Chem. 264: 106409. PMID: 32534374
    8. Drug-guided screening for pancreatic lipase inhibitors in functional foods.  |  Zhang, L., et al. 2021. Food Funct. 12: 4644-4653. PMID: 33912875
    9. Coffee simulated inhibition of pancreatic lipase and antioxidant activities: Effect of milk and decaffeination.  |  Jurema Soares, M., et al. 2022. Food Res Int. 160: 111730. PMID: 36076418
    10. Characterization of novel PNLIP variants in congenital pancreatic lipase deficiency.  |  Lin, J., et al. 2023. Pancreatology. 23: 1036-1040. PMID: 37926600

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Pancreatic Lipase Antibody (G-11)

    sc-393158
    200 µg/ml
    $322.00

    Pancreatic Lipase Antibody (G-11): m-IgG Fc BP-HRP Bundle

    sc-538158
    200 µg Ab; 10 µg BP
    $361.00

    Pancreatic Lipase Antibody (G-11): m-IgGκ BP-HRP Bundle

    sc-535718
    200 µg Ab; 40 µg BP
    $361.00

    Pancreatic Lipase Antibody (G-11): m-IgG2a BP-HRP Bundle

    sc-548221
    200 µg Ab; 10 µg BP
    $361.00

    Pancreatic Lipase (G-11) Neutralizing Peptide

    sc-393158 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393158 P appropriate for?

    Asked by: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Satisfactory Western blot data of PancreaticSatisfactory Western blot data of Pancreatic Lipase expression in rat pancreas and human pancreas tissue extracts.-SCBT QC
    Date published: 2014-04-03
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    Pancreatic Lipase Antibody (G-11) is rated 5.0 out of 5 by 1.
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