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Pancreatic Lipase Antibody (A-2): sc-393085

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Datasheets
  • Pancreatic Lipase Antibody (A-2) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 26-47 near the N-terminus of Pancreatic Lipase of rat origin
  • recommended for detection of Pancreatic Lipase of mouse and rat origin by WB, IP, IF and ELISA
  • available conjugated to agarose for IP
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546 or Alexa Fluor® 594 for IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Pancreatic Lipase Antibody (A-2) for WB applications. These reagents are now offered in bundles with Pancreatic Lipase Antibody (A-2) (see ordering information below).
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Pancreatic Lipase Antibody (A-2) is a mouse monoclonal IgG1 antibody that detects pancreatic lipase in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Pancreatic lipase is a critical enzyme in the digestive system, primarily located in the pancreas, where anti-pancreatic lipase antibody (A-2) helps study its vital role in the breakdown of dietary fats. By hydrolyzing triglycerides into diglycerides, monoglycerides, and free fatty acids, pancreatic lipase facilitates the absorption of these essential nutrients in the intestines. This process is crucial for maintaining energy balance and overall metabolic health, as pancreatic lipase allows the body to utilize fats effectively. The activity of pancreatic lipase is also influenced by various factors, including the presence of bile salts and colipase, which enhance its function, making pancreatic lipase (A-2) monoclonal antibody an important target for studying lipid metabolism and related disorders. Pancreatic lipase (A-2) antibody serves as an invaluable tool for researchers investigating the dynamics of lipid digestion and absorption, as well as the broader implications of lipid metabolism in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Pancreatic Lipase Antibody (A-2) References:

  1. Properties and function of pancreatic lipase related protein 2.  |  Lowe, ME. 2000. Biochimie. 82: 997-1004. PMID: 11099796
  2. Natural inhibitors of pancreatic lipase as new players in obesity treatment.  |  de la Garza, AL., et al. 2011. Planta Med. 77: 773-85. PMID: 21412692
  3. Canine and feline pancreatic lipase immunoreactivity.  |  Xenoulis, PG. and Steiner, JM. 2012. Vet Clin Pathol. 41: 312-24. PMID: 22861648
  4. The modulation of pancreatic lipase activity by alginates.  |  Wilcox, MD., et al. 2014. Food Chem. 146: 479-84. PMID: 24176371
  5. Computational approaches for the discovery of natural pancreatic lipase inhibitors as antiobesity agents.  |  Almasri, IM. 2020. Future Med Chem. 12: 741-757. PMID: 32212943
  6. Structure-activity relationship of dietary flavonoids on pancreatic lipase.  |  Li, MM., et al. 2023. Curr Res Food Sci. 6: 100424. PMID: 36618100
  7. Partial validation of the Vcheck canine pancreatic lipase assay.  |  Jakus, P., et al. 2023. Vet Clin Pathol. 52: 271-275. PMID: 36710504
  8. Methodologies for Assessing Pancreatic Lipase Catalytic Activity: A Review.  |  Rocha, S., et al. 2024. Crit Rev Anal Chem. 54: 3038-3065. PMID: 37335098
  9. Morin inhibits the activity of pancreatic lipase and adipogenesis.  |  V P, V., et al. 2024. Eur J Pharmacol. 977: 176705. PMID: 38830457
  10. Structure and function of pancreatic lipase and colipase.  |  Lowe, ME. 1997. Annu Rev Nutr. 17: 141-58. PMID: 9240923

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pancreatic Lipase Antibody (A-2)

sc-393085
200 µg/ml
$322.00

Pancreatic Lipase Antibody (A-2): m-IgG Fc BP-HRP Bundle

sc-538134
200 µg Ab; 10 µg BP
$361.00

Pancreatic Lipase Antibody (A-2): m-IgGκ BP-HRP Bundle

sc-535693
200 µg Ab; 40 µg BP
$361.00

Pancreatic Lipase Antibody (A-2): m-IgG1 BP-HRP Bundle

sc-545541
200 µg Ab; 20 µg BP
$361.00

Pancreatic Lipase Antibody (A-2) AC

sc-393085 AC
500 µg/ml, 25% agarose
$424.00

Pancreatic Lipase Antibody (A-2) Alexa Fluor® 488

sc-393085 AF488
200 µg/ml
$338.00

Pancreatic Lipase Antibody (A-2) Alexa Fluor® 546

sc-393085 AF546
200 µg/ml
$364.00

Pancreatic Lipase Antibody (A-2) Alexa Fluor® 594

sc-393085 AF594
200 µg/ml
$364.00

Pancreatic Lipase (A-2) Neutralizing Peptide

sc-393085 P
100 µg/0.5 ml
$69.00

What application is the blocking peptide sc-393085 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great Western blot data of Pancreatic LipaseGreat Western blot data of Pancreatic Lipase expression in rat pancreas and human pancreas tissue extracts. -SCBT QC
Date published: 2013-04-28
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Pancreatic Lipase Antibody (A-2) is rated 5.0 out of 5 by 1.
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