pan-Cytokeratin Antibody (K20): sc-53402
- pan-Cytokeratin Antibody (K20) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against hair keratin of human origin
- recommended for detection of broad range of Cytokeratin proteins of human origin by WB, IP, IF and IHC(P)
- See pan-Cytokeratin (C11): sc-8018 for pan-Cytokeratin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pan-Cytokeratin Antibody (K20) for WB and IHC(P) applications. These reagents are now offered in bundles with pan-Cytokeratin Antibody (K20) (see ordering information below).
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Pan-Cytokeratin Antibody (K20) is a mouse monoclonal IgG2a antibody that detects pan-Cytokeratin in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Pan-Cytokeratin is a crucial component of the cytoskeleton in epithelial cells, providing structural support and playing a significant role in maintaining cell shape and integrity. Pan-Cytokeratin is primarily located in the cytoplasm of epithelial cells, where pan-Cytokeratin forms a network of intermediate filaments that contribute to the mechanical resilience of tissues. Pan-Cytokeratin expression patterns can help differentiate between various types of epithelial tumors in cancer diagnostics. For instance, specific cytokeratin profiles can indicate the origin of metastatic tumors, aiding in the identification of primary sites and informing treatment strategies. Anti-pan-Cytokeratin antibody (K20) is an invaluable tool for researchers and clinicians seeking to understand epithelial cell biology and its implications in disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
pan-Cytokeratin Antibody (K20) References:
- Characterization of cultivated murine lacrimal gland epithelial cells. | Kobayashi, S., et al. 2012. Mol Vis. 18: 1271-7. PMID: 22665974
- [Angiomyolipoma with Epithelial Cysts (AMLEC) of the Kidney]. | Takei, K., et al. 2016. Hinyokika Kiyo. 62: 355-60. PMID: 27569353
- Comparative study of isolation, expansion and characterization of epithelial cells. | Gottipamula, S., et al. 2017. Cytotherapy. 19: 263-271. PMID: 27894881
- Detection of micro-metastases by flow cytometry in lymph nodes from patients with penile cancer. | Zhang, L., et al. 2018. BMC Urol. 18: 86. PMID: 30290760
- Microfluidic-Based Immunohistochemistry Combined With Next-Generation Sequencing on Diagnostic Tissue Sections for Detection of Tumoral BRAF V600E Mutation. | Leblond, AL., et al. 2019. Am J Clin Pathol. 152: 59-73. PMID: 31065676
- Immunohistochemical features of carcinoma ex pleomorphic adenoma and pleomorphic adenoma in the lacrimal gland. | Zhang, P., et al. 2019. Int J Ophthalmol. 12: 1238-1242. PMID: 31456912
- Immunohistochemical Characterization of Proliferative Lesions in the Thymus of Aging CD-1 Mice From Two Studies on the RITA Database, With Special Reference to the Perivascular Space. | Funk, J., et al. 2022. Toxicol Pathol. 50: 308-328. PMID: 35321614
- Immunohistochemical Stain-Aided Annotation Accelerates Machine Learning and Deep Learning Model Development in the Pathologic Diagnosis of Nasopharyngeal Carcinoma. | Lin, TP., et al. 2023. Diagnostics (Basel). 13: PMID: 38132269
- Poor patient outcome correlates with active engulfment of cytokeratin positive CTCs within cancer-associated monocyte population in lung cancer. | Wiegmans, AP., et al. 2024. Clin Exp Metastasis. 41: 219-228. PMID: 38416302
- Comparison of techniques for corneal epithelium cell culture for the collection of conditioned medium. | Viveiros, MMH., et al. 2024. Arq Bras Oftalmol. 87: e2022. PMID: 38655938
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan-Cytokeratin Antibody (K20) | sc-53402 | 200 µg/ml | $322.00 | |||
pan-Cytokeratin Antibody (K20): m-IgG Fc BP-HRP Bundle | sc-536956 | 200 µg Ab; 10 µg BP | $361.00 | |||
pan-Cytokeratin Antibody (K20): m-IgGκ BP-HRP Bundle | sc-534133 | 200 µg Ab; 40 µg BP | $361.00 |