Date published: 2025-11-26

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pan-Cytokeratin Antibody (B311.1): sc-58826

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Datasheets
  • pan-Cytokeratin Antibody (B311.1) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
  • raised against a pan-Cytokeratin fraction isolated from A-431 epidermoid carcinoma cell line of human origin
  • recommended for detection of Cytokeratin 4, 5, 6, 8, 10, 13 and 18 of mouse, rat, human and bovine origin by WB, IP, IF, IHC(P), FCM and ELISA
  • See pan-Cytokeratin (C11): sc-8018 for pan-Cytokeratin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pan-Cytokeratin Antibody (B311.1) for WB and IHC(P) applications. These reagents are now offered in bundles with pan-Cytokeratin Antibody (B311.1) (see ordering information below).

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pan-Cytokeratin Antibody (B311.1) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in mouse, rat, human, and bovine samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). pan-Cytokeratin is a crucial component of the cytoskeletal structure in epithelial cells, providing mechanical support and playing a vital role in maintaining cell shape and integrity. pan-Cytokeratin is primarily located in the cytoplasm of epithelial cells, where pan-Cytokeratin forms a network of intermediate filaments that contribute to the overall architecture of tissues. This structural role is particularly important in the context of tissue resilience and protection against mechanical stress, which is essential for the proper functioning of epithelial tissues. Additionally, pan-Cytokeratin serves as a valuable biomarker for identifying and characterizing various types of epithelial tumors, as pan-Cytokeratin expression patterns can indicate the differentiation status of malignant cells. For instance, specific cytokeratin isoforms are often upregulated in certain carcinomas, making pan-Cytokeratin (B311.1) antibody a key tool in cancer diagnostics and research.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

pan-Cytokeratin Antibody (B311.1)

sc-58826
200 µg/ml
$316.00

pan-Cytokeratin Antibody (B311.1): m-IgG Fc BP-HRP Bundle

sc-537156
200 µg Ab; 10 µg BP
$354.00

pan-Cytokeratin Antibody (B311.1): m-IgGκ BP-HRP Bundle

sc-534352
200 µg Ab; 40 µg BP
$354.00

pan-Cytokeratin Antibody (B311.1): m-IgG1 BP-HRP Bundle

sc-545041
200 µg Ab; 20 µg BP
$354.00

Can pan-Cytokeratin (B311.1): sc-58826 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: jerojero
Thank you for your question. Yes, pan-Cytokeratin (B311.1): sc-58826 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Works well for WB with HeLa whole cell lysateWorks well for WB with HeLa whole cell lysate. -SCBT QC
Date published: 2015-02-25
Rated 5 out of 5 by from Good quality antibody for human paraffin samplesGood quality antibody for human paraffin samples. Specific and sensitive -SCBT QC
Date published: 2015-02-01
Rated 5 out of 5 by from Satisfactory WB in Hep G2 (A) and SW480 (B)Satisfactory WB in Hep G2 (A) and SW480 (B) whole cell lysates. -SCBT QC
Date published: 2014-08-08
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pan-Cytokeratin Antibody (B311.1) is rated 5.0 out of 5 by 3.
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