Pan beta Tubulin Antibody (C-10): sc-398937

Pan β Tubulin Antibody (C-10) is a mouse monoclonal IgG1 kappa light chain antibody designed to recognize multiple isoforms of β Tubulin, including β1, β2A, β2B, β2C, β3, β4, β5, β6, and β8, across mouse, rat, and human species. β Tubulin, also known as tubulin beta chain or TUBB, is a crucial component of the cytoskeleton, forming heterodimers with α Tubulin to assemble into microtubule filaments that are essential for maintaining cell structure, facilitating intracellular transport, and ensuring accurate cell division. The structural integrity of microtubules is vital for numerous cellular processes, and β Tubulin interacts with a variety of proteins such as motor proteins kinesin and dynein, as well as microtubule-associated proteins (MAPs) like tau and MAP2, which regulate microtubule stability and dynamics. By targeting an internal epitope within amino acids 209-305 of human β4 Tubulin, anti-β Tubulin antibody (C-10) ensures broad reactivity and high affinity, making it an invaluable tool for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). β Tubulin (C-10) antibody′s ability to detect multiple β Tubulin isoforms allows researchers to study cytoskeletal organization, cell motility, and the complex network of protein interactions that govern cellular architecture and function. Accurate detection and visualization of β Tubulin with β Tubulin monoclonal antibody (C-10) enable the exploration of microtubule dynamics and the roles of β Tubulin-interacting proteins in both normal cellular processes and pathological conditions such as cancer, neurodegenerative diseases, and developmental disorders.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Pan beta Tubulin Antibody (C-10) has 13 citations in a variety of scientific publications.

Primary antibodies like Anti-Pan beta Tubulin Antibody (C-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Pan beta Tubulin Antibody (C-10) Specifications

Alternate Product Name: Pan β Tubulin

Product Clone Name: C-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 209-305

Epitope Target: β4 Tubulin

Epitope Species: human

Product Reactivity/Detection: β1, β2A, β2B, β2C, β3, β4, β5, β6 and β8 Tubulin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 13 citations in various scientific publications

Available Conjugates/Forms for Pan beta Tubulin Antibody (C-10): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred beta Tubulin antibody is beta Tubulin Antibody (D-10): sc-5274.