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Paip1 Antibody (E-7) is a mouse monoclonal IgG2b kappa light chain antibody that detects Paip1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-Paip1 antibody (E-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Paip1, known as PABP-interacting protein, plays a crucial role in translation regulation by binding to polyadenylate-binding protein (PABP). This interaction enhances mRNA stability and translation efficiency, which is vital for proper gene expression and cellular function. Paip1 competes with Paip2 for binding to PABP; while Paip1 stimulates translation, Paip2 acts as a repressor by decreasing PABP′s affinity for polyadenylate RNA. The human Paip1 gene encodes a 480 amino acid protein featuring an eIF4A-binding region and a proline-rich N terminus, which are essential for linking mRNA termini and facilitating translation initiation. Paip1 overexpression in COS-7 cells stimulates translation, highlighting its importance in protein synthesis regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Paip1 Antibody (E-7) | sc-365687 | 200 µg/ml | $316.00 | |||
Paip1 Antibody (E-7): m-IgGκ BP-HRP Bundle | sc-522330 | 200 µg Ab, 40 µg BP | $354.00 | |||
Paip1 Antibody (E-7): m-IgG2b BP-HRP Bundle | sc-549021 | 200 µg Ab; 10 µg BP | $354.00 | |||
Paip1 Antibody (E-7) AC | sc-365687 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Paip1 Antibody (E-7) HRP | sc-365687 HRP | 200 µg/ml | $316.00 | |||
Paip1 Antibody (E-7) FITC | sc-365687 FITC | 200 µg/ml | $330.00 | |||
Paip1 Antibody (E-7) PE | sc-365687 PE | 200 µg/ml | $343.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 488 | sc-365687 AF488 | 200 µg/ml | $357.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 546 | sc-365687 AF546 | 200 µg/ml | $357.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 594 | sc-365687 AF594 | 200 µg/ml | $357.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 647 | sc-365687 AF647 | 200 µg/ml | $357.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 680 | sc-365687 AF680 | 200 µg/ml | $357.00 | |||
Paip1 Antibody (E-7) Alexa Fluor® 790 | sc-365687 AF790 | 200 µg/ml | $357.00 |