p55 Antibody (A-4): sc-376480
- p55 Antibody (A-4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 320-376 mapping within an internal region of erythrocyte membrane protein p55 of human origin
- recommended for detection of erythrocyte membrane protein p55 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for p55 Antibody (A-4) for WB applications. These reagents are now offered in bundles with p55 Antibody (A-4) (see ordering information below).
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SEE ALSO...
p55 Antibody (A-4) is a mouse monoclonal IgG1 antibody that detects p55 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p55 is an extensively palmitoylated erythrocyte membrane protein and a member of the MAGUK family, known for its critical role in maintaining the structural integrity and functionality of the erythrocyte membrane. p55 (A-4) antibody recognizes a protein structure that includes a PDZ/DHR domain, a conserved SH-3 domain that inhibits the tyrosine kinase activity of various oncoproteins, and a guanylate kinase-like domain, which collectively contribute to its ability to interact with other key proteins such as glycophorin C and 4.1R. These interactions are vital for the dynamic regulation of the erythrocyte membrane, influencing processes such as cell shape and stability. Additionally, p55 gene expression is associated with a CpG island, and p55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis, showing a two-fold amplification upon induction. anti-p55 antibody (A-4) is an essential tool for researchers studying erythrocyte biology and related pathologies, providing insights into p55′s function and implications in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p55 Antibody (A-4) | sc-376480 | 200 µg/ml | $322.00 | |||
p55 Antibody (A-4): m-IgG Fc BP-HRP Bundle | sc-540581 | 200 µg Ab; 10 µg BP | $361.00 | |||
p55 Antibody (A-4): m-IgG1 BP-HRP Bundle | sc-542220 | 200 µg Ab; 20 µg BP | $361.00 |