p53R2 Antibody (H-3): sc-137173

p53R2 Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody, designed to target the p53R2 protein, also known as R2, of human origin. p53R2 monoclonal antibody (H-3) recognizes an epitope comprising amino acids 52-351 at the C-terminus of p53R2, ensuring precise and reliable binding for accurate detection in various assays. p53R2 is a critical subunit of ribonucleotide reductase, an enzyme essential for the synthesis of deoxyribonucleoside triphosphates (dNTPs) necessary for DNA repair and replication. Under normal cellular conditions, p53R2 is predominantly located in the cytoplasm, but in response to DNA damage, p53R2 translocates to the nucleus where p53R2 supplies dNTPs required for effective DNA repair mechanisms. This dynamic localization is vital for maintaining genomic stability and enabling cells to respond appropriately to genotoxic stress. Anti-p53R2 antibody (H-3) demonstrates broad species reactivity, effectively recognizing p53R2 from mouse, rat, and human origins across multiple applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p53R2 (H-3) antibody is recommended for researchers studying cell cycle regulation, DNA synthesis, repair processes, and molecular pathways involved in tumor suppression. By facilitating reliable detection of p53R2, anti-p53R2 antibody (H-3) supports advancements in understanding p53R2′s role in cancer development and therapeutic responses. Whether employed in basic research or clinical studies, p53R2 monoclonal antibody (H-3) offers exceptional quality and performance to meet diverse experimental needs, making p53R2 (H-3) antibody a crucial reagent in molecular biology research.

The preferred R2 antibody is R2 Antibody (A-5): sc-398294.