P2X5 Antibody (H-5): sc-365036
- P2X5 Antibody (H-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 332-421 mapping at the C-terminus of P2X5 of human origin
- Anti-P2X5 Antibody (H-5) is recommended for detection of P2X5 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-P2X5 Antibody (H-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for P2X5 Antibody (H-5) for WB applications. These reagents are now offered in bundles with P2X5 Antibody (H-5) (see ordering information below).
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P2X5 Antibody (H-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects P2X5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-P2X5 antibody (H-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. P2X5 is a member of the P2X receptor family, which consists of ligand-gated ion channels that facilitate calcium ion influx in response to extracellular ATP. P2X5 receptors play a crucial role in mediating synaptic transmission and are expressed in diverse tissues such as neurons, prostate, bladder, pancreas, colon, testis, and ovary. P2X5 is involved in forming both homomeric and heteromeric channels, which are essential for various physiological processes. P2X5′s structure, characterized by intracellular amino- and carboxy-termini, influences receptor response to ATP and calcium permeability regulation. P2X5 dysregulation has been implicated in pathological conditions, including necrosis and apoptosis, highlighting P2X5′s importance in cellular signaling and health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
P2X5 Antibody (H-5) References:
- Cytolytic P2X purinoceptors. | Di Virgilio, F., et al. 1998. Cell Death Differ. 5: 191-9. PMID: 10200464
- Allosteric modulation and accelerated resensitization of human P2X(3) receptors by cibacron blue. | Alexander, K., et al. 1999. J Pharmacol Exp Ther. 291: 1135-42. PMID: 10565834
- Inactivation of P2X2 purinoceptors by divalent cations. | Ding, S. and Sachs, F. 2000. J Physiol. 522 Pt 2: 199-214. PMID: 10639098
- Evidence for P2X(3), P2X(4), P2X(5) but not for P2X(7) containing purinergic receptors in Müller cells of the rat retina. | Jabs, R., et al. 2000. Brain Res Mol Brain Res. 76: 205-10. PMID: 10762695
- A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue. | Oury, C., et al. 2000. J Biol Chem. 275: 22611-4. PMID: 10816552
- P2X receptors in sensory neurones. | Burnstock, G. 2000. Br J Anaesth. 84: 476-88. PMID: 10823099
- Pharmacology of cloned P2X receptors. | North, RA. and Surprenant, A. 2000. Annu Rev Pharmacol Toxicol. 40: 563-80. PMID: 10836147
- The human P2x1 receptor: molecular cloning, tissue distribution, and localization to chromosome 17. | Longhurst, PA., et al. 1996. Biochim Biophys Acta. 1308: 185-8. PMID: 8809107
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
P2X5 Antibody (H-5) | sc-365036 | 200 µg/ml | $322.00 | |||
P2X5 Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-529303 | 200 µg Ab; 10 µg BP | $361.00 | |||
P2X5 Antibody (H-5): m-IgGκ BP-HRP Bundle | sc-522125 | 200 µg Ab, 40 µg BP | $361.00 | |||
P2X5 Antibody (H-5): m-IgG1 BP-HRP Bundle | sc-543441 | 200 µg Ab; 20 µg BP | $361.00 | |||
P2X5 Antibody (H-5) AC | sc-365036 AC | 500 µg/ml, 25% agarose | $424.00 | |||
P2X5 Antibody (H-5) HRP | sc-365036 HRP | 200 µg/ml | $322.00 | |||
P2X5 Antibody (H-5) FITC | sc-365036 FITC | 200 µg/ml | $336.00 | |||
P2X5 Antibody (H-5) PE | sc-365036 PE | 200 µg/ml | $349.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 488 | sc-365036 AF488 | 200 µg/ml | $364.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 546 | sc-365036 AF546 | 200 µg/ml | $364.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 594 | sc-365036 AF594 | 200 µg/ml | $364.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 647 | sc-365036 AF647 | 200 µg/ml | $364.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 680 | sc-365036 AF680 | 200 µg/ml | $364.00 | |||
P2X5 Antibody (H-5) Alexa Fluor® 790 | sc-365036 AF790 | 200 µg/ml | $364.00 |