Date published: 2025-11-4

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p120 Antibody (6H11): sc-23873

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Datasheets
  • p120 Antibody (6H11) is a mouse monoclonal IgG1 κ p120 antibody, cited in 24 publications, provided at 200 µg/ml
  • raised against amino acids 8-349 of mouse p120
  • p120 Antibody (6H11) is recommended for detection of p120 of mouse, rat, human, canine and avian origin by WB, IP, IF and IHC(P)
  • Anti-p120 Antibody (6H11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p120 Antibody (6H11) for WB and IHC(P) applications. These reagents are now offered in bundles with p120 Antibody (6H11) (see ordering information below).

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p120 Antibody (6H11) is a mouse monoclonal IgG1 kappa light chain antibody that detects p120 protein of mouse, rat, human, canine, and avian origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. anti-p120 antibody (6H11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. p120 protein, also known as CTNND1, plays a crucial role in cellular adhesion by interacting with the cytoplasmic tail of E-cadherin, a key component in maintaining epithelial integrity. This interaction is vital for the formation of adherens junctions, which are essential for tissue architecture and cellular communication. Additionally, p120 regulates the stability and localization of E-cadherin at the cell membrane, thereby influencing cell signaling pathways that govern cell proliferation and differentiation. p120′s ability to modulate E-cadherin levels highlights its importance in cancer biology, as alterations in cadherin-mediated adhesion can lead to increased invasiveness and metastasis in tumor cells. p120 (6H11) monoclonal antibody enables researchers to gain insights into the mechanisms of cell adhesion and the potential implications for cancer progression and treatment.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p120 Antibody (6H11)

sc-23873
200 µg/ml
$316.00

p120 Antibody (6H11): m-IgG Fc BP-HRP Bundle

sc-528377
200 µg Ab; 10 µg BP
$354.00

p120 Antibody (6H11): m-IgGκ BP-HRP Bundle

sc-520739
200 µg Ab, 40 µg BP
$354.00

p120 Antibody (6H11): m-IgG1 BP-HRP Bundle

sc-542904
200 µg Ab; 20 µg BP
$354.00

p120 Antibody (6H11) AC

sc-23873 AC
500 µg/ml, 25% agarose
$416.00

p120 Antibody (6H11) HRP

sc-23873 HRP
200 µg/ml
$316.00

p120 Antibody (6H11) FITC

sc-23873 FITC
200 µg/ml
$330.00

p120 Antibody (6H11) PE

sc-23873 PE
200 µg/ml
$343.00

p120 Antibody (6H11) Alexa Fluor® 488

sc-23873 AF488
200 µg/ml
$357.00

p120 Antibody (6H11) Alexa Fluor® 546

sc-23873 AF546
200 µg/ml
$357.00

p120 Antibody (6H11) Alexa Fluor® 594

sc-23873 AF594
200 µg/ml
$357.00

p120 Antibody (6H11) Alexa Fluor® 647

sc-23873 AF647
200 µg/ml
$357.00

p120 Antibody (6H11) Alexa Fluor® 680

sc-23873 AF680
200 µg/ml
$357.00

p120 Antibody (6H11) Alexa Fluor® 790

sc-23873 AF790
200 µg/ml
$357.00

Can p120 (6H11): sc-23873 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: AbPolly
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, p120 (6H11): sc-23873 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_10, d_14, h_6CST
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Rated 5 out of 5 by from Good for WBThis antibody works very well for WB, the dilution ratio is 1:500.
Date published: 2018-03-16
Rated 5 out of 5 by from specific/sharp bands detectedThis antibody was tested on human aortic endothelial cells post various treatments. It gives specific band with no background.
Date published: 2017-09-14
Rated 5 out of 5 by from p120 reviewI used the p120 (6H11) antibody for western blotting at a 1:500 dilution and got a good signal when I was doing an IP and checking for the signal in total lysate.
Date published: 2017-08-25
Rated 5 out of 5 by from strong band at 120kdaStrong, reliable and specific, a great antibody for all your p120 detection needs,with specific band at 120kda.
Date published: 2017-05-31
Rated 5 out of 5 by from Good antibodythis antibody works well for IHC on human tissue of paraffin section at a 1:500 dilution
Date published: 2017-02-21
Rated 4 out of 5 by from Strip is not clear.Last year I purchased p120 sc-23873 sample. When doing human umbilical vein endothelial cells protein blotting, the results in the band is not very clear.I will try immunohistochemistry later.
Date published: 2017-02-21
Rated 5 out of 5 by from Highly recommended p120 monoclonalThis is the best p120 monoclonal antibody for a variety of application and species. Great clean strong bands in WB on MDCK, NRK, PC-12, EOC 20 and AMJ2-C8 whole cell lysates. Beautiful immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder and human bronchus tissue.
Date published: 2017-01-20
Rated 5 out of 5 by from Works wellImmunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization,dyeing effect is very good, recommend the use of.
Date published: 2016-12-17
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p120 Antibody (6H11) is rated 4.6 out of 5 by 14.
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