P-Selectin/CD62P/SELP Antibody (P8G6): sc-18834
- P-Selectin/CD62P/SELP Antibody (P8G6) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against IL-1β activated HUV-EC cells expressing full length P-Selectin
- recommended for detection of P-Selectin of human origin by IP, IF, IHC(P), FCM and ELISA
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for inhibiting P-Selectin dependent interactions and inhibiting platelet binding to monocytes, sc-18834 L, 200 µg/0.1 ml
- See P-Selectin/CD62P/SELP (CTB201): sc-8419 for P-Selectin/CD62P/SELP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for P-Selectin/CD62P/SELP Antibody (P8G6) for IHC(P) applications. These reagents are now offered in bundles with P-Selectin/CD62P/SELP Antibody (P8G6) (see ordering information below).
QUICK LINKS
P-Selectin Antibody (P8G6) is a mouse monoclonal IgG1 antibody that detects P-Selectin in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). P-Selectin, also known as GMP-140 or CD62P, plays a crucial role in the inflammatory response by mediating the adhesion of leukocytes to activated endothelial cells and platelets, which is essential for the recruitment of immune cells to sites of injury or infection. P-Selectin (P8G6) antibody recognizes this protein primarily on the surface of activated platelets and endothelial cells, where P-Selectin facilitates the initial stages of leukocyte rolling and adhesion, a critical process in the immune response. The interaction of P-Selectin with its ligands, such as sialylated carbohydrates on neutrophils and monocytes, is vital for effective immune surveillance and response, highlighting its importance in both normal physiology and pathological conditions, such as thrombosis and inflammation. Anti-P-Selectin antibody (P8G6) serves as an invaluable tool for researchers studying these processes, providing insights into the mechanisms of cell adhesion and the role of selectins in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
P-Selectin/CD62P/SELP Antibody (P8G6) | sc-18834 | 200 µg/ml | $322.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6): m-IgG Fc BP-HRP Bundle | sc-536596 | 200 µg Ab; 10 µg BP | $361.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6): m-IgGκ BP-HRP Bundle | sc-533750 | 200 µg Ab; 40 µg BP | $361.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6): m-IgG1 BP-HRP Bundle | sc-544696 | 200 µg Ab; 20 µg BP | $361.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6) FITC | sc-18834 FITC | 200 µg/ml | $336.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6) L | sc-18834 L | 200 µg/0.1 ml | $322.00 | |||
P-Selectin/CD62P/SELP Antibody (P8G6) PE | sc-18834 PE | 200 µg/ml | $349.00 |