p-PKC theta Antibody (A-4): sc-271920

p-PKC θ Antibody (A-4) is a mouse monoclonal IgG1 antibody that detects p-PKC θ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p-PKC θ is a member of the protein kinase C (PKC) family, which plays a crucial role in regulating various cellular functions, including cell growth, differentiation, and gene expression. p-PKC θ is primarily located in the cytoplasm and translocates to the membrane upon activation, which is essential for function in signal transduction pathways. Proper localization of p-PKC θ allows interaction with specific substrates and participation in downstream signaling cascades that influence cellular responses to external stimuli. p-PKC θ undergoes post-translational modifications, such as phosphorylation, which can further modulate activity and interactions. Phosphorylation of specific residues, including Serine 676 and Serine 695, regulates p-PKC θ′s ability to activate transcription factors like NFκB, thereby impacting immune responses and inflammation. With a critical role in cellular signaling and regulation, anti-p-PKC θ antibody (A-4) serves as an invaluable tool for researchers studying the intricate mechanisms of cell signaling and the pathophysiology of various diseases.

The preferred PKC antibody is PKC Antibody (A-3): sc-17769.