p-p120 Antibody (pY96.6A): sc-293017

p-p120 Antibody (pY96.6A) is a mouse monoclonal IgG1 antibody that detects p120 in mouse, rat, and human samples through western blotting (WB). Anti-p120 antibody (pY96.6A) specifically recognizes the phosphorylated form of p120, a crucial protein that plays a significant role in cellular adhesion and signaling pathways. Located primarily in the cytoplasm, nucleus, and cell membrane, p120 is essential for mediating interactions between cadherins and catenins, which are vital for maintaining tissue integrity and regulating cell behavior. The phosphorylation of p120, particularly at tyrosine residues, modulates interactions with other proteins and influences downstream signaling pathways, including those activated by epidermal growth factor and platelet-derived growth factor receptors. This post-translational modification can affect cellular processes such as proliferation, migration, and differentiation, making p120 a key player in various physiological and pathological conditions. With interactions across multiple signaling molecules and involvement in critical cellular functions, p120 serves as a valuable target for research in cancer biology and developmental studies.

The preferred p120 antibody is p120 Antibody (15D2): sc-23872.