p-NFATc3 Antibody (H-2): sc-365883
- p-NFATc3 Antibody (H-2) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- Anti-p-NFATc3 Antibody (H-2) is recommended for detection of Ser 169 phosphorylated NFATc3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-p-NFATc3 Antibody (H-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-NFATc3 Antibody (H-2). This work is in progress.
p-NFATc3 Antibody (H-2) is a mouse monoclonal IgG2b kappa light chain antibody that detects Ser 169 phosphorylated NFATc3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p-NFATc3 (H-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NFATc3, a member of the NFAT (nuclear factor of activated T cells) family, plays a crucial role in regulating gene expression in response to calcium signaling in T cells, which is vital for immune responses. NFATc3 is primarily located in the cytosol and nucleus, where NFATc3 undergoes a significant conformational change upon dephosphorylation by calcineurin, allowing NFATc3 to translocate into the nucleus and activate transcription of cytokine genes. This dynamic localization and modification are essential for the timely and appropriate activation of immune responses, highlighting NFATc3′s importance in both normal immune function and potential pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-NFATc3 Antibody (H-2) | sc-365883 | 200 µg/ml | $316.00 | |||
p-NFATc3 Antibody (H-2) AC | sc-365883 AC | 500 µg/ml, 25% agarose | $416.00 | |||
p-NFATc3 Antibody (H-2) HRP | sc-365883 HRP | 200 µg/ml | $316.00 | |||
p-NFATc3 Antibody (H-2) FITC | sc-365883 FITC | 200 µg/ml | $330.00 | |||
p-NFATc3 Antibody (H-2) PE | sc-365883 PE | 200 µg/ml | $343.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 488 | sc-365883 AF488 | 200 µg/ml | $357.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 546 | sc-365883 AF546 | 200 µg/ml | $357.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 594 | sc-365883 AF594 | 200 µg/ml | $357.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 647 | sc-365883 AF647 | 200 µg/ml | $357.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 680 | sc-365883 AF680 | 200 µg/ml | $357.00 | |||
p-NFATc3 Antibody (H-2) Alexa Fluor® 790 | sc-365883 AF790 | 200 µg/ml | $357.00 | |||
p-NFATc3 (H-2) Neutralizing Peptide | sc-365883 P | 100 µg/0.5 ml | $68.00 |