osteocalcin Antibody (ABOC-5021): sc-73464

Osteocalcin Antibody (ABOC-5021) is a mouse monoclonal IgG1 antibody that detects osteocalcin of human and bovine origin by western blotting (WB), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-osteocalcin antibody (ABOC-5021) is available in a non-conjugated form, specifically designed for osteocalcin applications. Osteocalcin, also known as BGLAP or BGP, is a crucial non-collagenous protein found in bone, primarily produced by osteoblasts. Osteocalcin plays a significant role in bone mineralization and calcium homeostasis, as osteocalcin binds to hydroxyapatite in a calcium-dependent manner, facilitating the mineralization process during bone formation. Osteocalcin is particularly important during embryonic development, appearing transiently at the time of mineral deposition, indicating a vital function in skeletal development. Additionally, osteocalcin is one of the most abundant proteins in mineralized adult bone, and genetic variations at the osteocalcin locus on chromosome 1q have been linked to variations in postmenopausal bone mineral density, potentially influencing the risk of osteoporosis in women. With a critical role in bone health and metabolism, osteocalcin remains a key target for research in bone biology and related disorders.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-osteocalcin Antibody (ABOC-5021) has 21 citations in a variety of scientific publications.

Primary antibodies like Anti-osteocalcin Antibody (ABOC-5021) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

osteocalcin Antibody (ABOC-5021) Specifications

Alternate Product Name: osteocalcin

Product Clone Name: ABOC-5021

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: osteocalcin

Epitope Species: bovine

Product Reactivity/Detection: osteocalcin

Species Reactivity/Detection: human, bovine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide, 0.1% gelatin and 1% glycerol

Research Citations: 21 citations in various scientific publications

Available Conjugates/Forms for osteocalcin Antibody (ABOC-5021): N/A

The preferred osteocalcin antibody is osteocalcin Antibody (D-11): sc-390877.