Orai2 Antibody (C-12): sc-376749
- Orai2 Antibody (C-12) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-49 mapping at the N-terminus of Orai2 of human origin
- recommended for detection of Orai2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for Orai2 Antibody (C-12) for WB applications. These reagents are now offered in bundles with Orai2 Antibody (C-12) (see ordering information below).
QUICK LINKS
Orai2 Antibody (C-12) is a mouse monoclonal IgG2b antibody that detects Orai2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Orai2, also known as CBCIP2 or TMEM142B, is a 254 amino acid multi-pass membrane protein that is crucial for store-operated calcium entry, a vital process that facilitates calcium influx and replenishes calcium stores that have been depleted by inositol 1,4,5-trisphosphate and other calcium-mobilizing agents. Orai2 is primarily located in the plasma membrane, where Orai2 plays a significant role in mediating calcium influx through calcium release-activated calcium (CRAC) channels, particularly in T-cells, which are essential for the immune response. The interaction of Orai2 with the calcium sensor Stim1 enhances the calcium-selective current, underscoring Orai2′s importance in maintaining cellular calcium homeostasis and regulating various physiological processes. Anti-Orai2 antibody (C-12) is an invaluable tool for researchers studying calcium signaling pathways and their implications in immune function and other cellular activities.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Orai2 Antibody (C-12) | sc-376749 | 200 µg/ml | $322.00 | |||
Orai2 Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-540638 | 200 µg Ab; 10 µg BP | $361.00 | |||
Orai2 Antibody (C-12): m-IgG2b BP-HRP Bundle | sc-549790 | 200 µg Ab; 10 µg BP | $361.00 |