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OPLAH Antibody (C-6): sc-393570

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Datasheets
  • OPLAH Antibody (C-6) is a mouse monoclonal IgG2a κ OPLAH antibody provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 1263-1286 at the C-terminus of OPLAH of human origin
  • OPLAH Antibody (C-6) is recommended for detection of OPLAH of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • Anti-OPLAH Antibody (C-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for OPLAH Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with OPLAH Antibody (C-6) (see ordering information below).
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    OPLAH Antibody (C-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects OPLAH protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-OPLAH antibody (C-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. OPLAH protein, also known as 5-oxoprolinase, plays a critical role in the gamma-glutamyl cycle, which is essential for the synthesis and metabolism of glutathione, a key antioxidant that regulates amino acid transport and protects cells from oxidative stress. This enzyme catalyzes the conversion of 5-oxo-L-proline to L-glutamate, a reaction coupled with ATP hydrolysis, highlighting OPLAH′s importance in cellular energy metabolism and amino acid homeostasis. OPLAH functions as a 1,288 amino acid homodimer and is predominantly expressed in the kidney, with lower expression levels found in the lung, breast, colon, and ovary. The gene encoding OPLAH is located on human chromosome 8, which is associated with various diseases, including schizophrenia, bipolar disorder, and congenital hypothyroidism, underscoring OPLAH′s potential relevance in both health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    OPLAH Antibody (C-6)

    sc-393570
    200 µg/ml
    $322.00

    OPLAH Antibody (C-6): m-IgG Fc BP-HRP Bundle

    sc-530501
    200 µg Ab; 10 µg BP
    $361.00

    OPLAH Antibody (C-6): m-IgGκ BP-HRP Bundle

    sc-524002
    200 µg Ab, 40 µg BP
    $361.00

    OPLAH Antibody (C-6): m-IgG2a BP-HRP Bundle

    sc-547510
    200 µg Ab; 10 µg BP
    $361.00

    OPLAH Antibody (C-6) AC

    sc-393570 AC
    500 µg/ml, 25% agarose
    $424.00

    OPLAH Antibody (C-6) HRP

    sc-393570 HRP
    200 µg/ml
    $322.00

    OPLAH Antibody (C-6) FITC

    sc-393570 FITC
    200 µg/ml
    $336.00

    OPLAH Antibody (C-6) PE

    sc-393570 PE
    200 µg/ml
    $349.00

    OPLAH Antibody (C-6) Alexa Fluor® 488

    sc-393570 AF488
    200 µg/ml
    $364.00

    OPLAH Antibody (C-6) Alexa Fluor® 546

    sc-393570 AF546
    200 µg/ml
    $364.00

    OPLAH Antibody (C-6) Alexa Fluor® 594

    sc-393570 AF594
    200 µg/ml
    $364.00

    OPLAH Antibody (C-6) Alexa Fluor® 647

    sc-393570 AF647
    200 µg/ml
    $364.00

    OPLAH Antibody (C-6) Alexa Fluor® 680

    sc-393570 AF680
    200 µg/ml
    $364.00

    OPLAH Antibody (C-6) Alexa Fluor® 790

    sc-393570 AF790
    200 µg/ml
    $364.00

    OPLAH (C-6) Neutralizing Peptide

    sc-393570 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393570 P appropriate for?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_4, d_30, h_22CST
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    Rated 5 out of 5 by from Satisfactory Western blot data of OPLAH expressionSatisfactory Western blot data of OPLAH expression in non-transfected 293T, human OPLAH transfected 293T K-562 and Hep G2 whole cell lysates. -SCBT QC
    Date published: 2013-04-30
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    OPLAH Antibody (C-6) is rated 5.0 out of 5 by 1.
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