Anti-Nup93 Antibody (E-8) is a mouse monoclonal IgG1 (kappa light chain) Nup93 antibody provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of Nup93 of human origin
Anti-Nup93 Antibody (E-8) is recommended for detection of Nup93 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Nup93 Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Nup93 (E-8): sc-374399.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Nup93 Antibody (E-8) is a high quality monoclonal Nup93 antibody (also designated Nup93 antibody) suitable for the detection of the Nup93 protein of mouse, rat and human origin. Nup93 Antibody (E-8) is available as both the non-conjugated anti-Nup93 antibody form, as well as multiple conjugated forms of anti-Nup93 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup93 (nucleoporin 93) is the most abundant nucleoporin found per NPC, contributing over 10% of the mass. It localizes to the nuclear side of the NPC, predominantly in the basket terminal ring area, and exists in a complex with Nup188, Nup53 and Nup205. This complex is crucial for NPC stability and proper assembly. Nup93 interacts directly with the Nup62 complex located at the center of the NPC and thus tethers the two subcomplexes. Nup93 is composed of a coiled-coil domain at its N-terminus and a C-terminal helical domain. Its proper function is essential for cell viability and normal NPC function.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can Nup93 (E-8): sc-374399 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: jerojero
Thank you for your question. Yes, Nup93 (E-8): sc-374399 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Thank you for your question.
For detailed protocol information, please refer to our online protocol here:
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