Nrl Antibody (G-6): sc-166087
- Nrl Antibody (G-6) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 11-46 near the N-terminus of Nrl of human origin
- recommended for detection of Nrl of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- TransCruz reagent for ChIP application (sc-166087 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for Nrl Antibody (G-6) for WB and IHC(P) applications. These reagents are now offered in bundles with Nrl Antibody (G-6) (see ordering information below).
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SEE ALSO...
Nrl Antibody (G-6) is a mouse monoclonal IgG2b antibody that detects Nrl in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Nrl, or neural retina leucine zipper, is a crucial transcription factor belonging to the Maf family, characterized by its highly conserved basic leucine zipper (bZIP) DNA-binding motif. Nrl plays a vital role in retinal development and function, particularly in regulating photoreceptor cell differentiation and rhodopsin expression, a key protein for vision. Nrl achieves this by binding to specific response elements in the rhodopsin promoter, thereby influencing the transcription of genes essential for phototransduction. Additionally, Nrl is expressed throughout the developing central and peripheral nervous systems, highlighting its importance in neuronal differentiation. In adulthood, Nrl expression is primarily localized to neocortex, brainstem, and retinal neurons, underscoring its role in maintaining visual system functionality. anti-Nrl antibody (G-6) is an invaluable tool for researchers studying retinal development and related disorders, providing insights into molecular mechanisms underlying vision and potential therapeutic targets for retinal diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nrl Antibody (G-6) | sc-166087 | 200 µg/ml | $316.00 | |||
Nrl Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-540012 | 200 µg Ab; 10 µg BP | $354.00 | |||
Nrl Antibody (G-6): m-IgG2b BP-HRP Bundle | sc-549766 | 200 µg Ab; 10 µg BP | $354.00 | |||
Nrl (G-6) Neutralizing Peptide | sc-166087 P | 100 µg/0.5 ml | $68.00 | |||
Nrl Antibody (G-6) X | sc-166087 X | 200 µg/0.1 ml | $316.00 |