NPY5-R Antibody (H-4): sc-137167
- NPY5-R Antibody (H-4) is a mouse monoclonal IgG2b κ NPY5-R antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 33-68 within an extracellular domain of NPY5-R of human origin
- NPY5-R Antibody (H-4) is recommended for detection of NPY5-R of human origin by WB, IP, IF and ELISA
- Anti-NPY5-R Antibody (H-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NPY5-R Antibody (H-4) for WB applications. These reagents are now offered in bundles with NPY5-R Antibody (H-4) (see ordering information below).
NPY5-R Antibody (H-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects NPY5-R protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-NPY5-R antibody (H-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NPY5-R protein plays a crucial role in regulating feeding behavior and energy homeostasis, as NPY5-R is involved in signaling pathways of neuropeptides that influence appetite and satiety. NPY5-R is primarily localized in the paraventricular hypothalamic nucleus and lateral hypothalamus, areas of the brain integral to food intake control. NPY5-R gene is located on human chromosome 4q32.2, and NPY5-R expression is essential for maintaining energy balance, making NPY5-R a significant target for research into obesity and metabolic disorders. Additionally, NPY5-R shares structural similarities with other neuropeptide Y receptors, such as NPY1-R, NPY2-R, and NPY4-R, which further underscores NPY5-R importance in neuroendocrine signaling.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NPY5-R Antibody (H-4) References:
- Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. | Bard, JA., et al. 1995. J Biol Chem. 270: 26762-5. PMID: 7592911
- A receptor subtype involved in neuropeptide-Y-induced food intake. | Gerald, C., et al. 1996. Nature. 382: 168-71. PMID: 8700207
- Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior. | Hu, Y., et al. 1996. J Biol Chem. 271: 26315-9. PMID: 8824284
- Inactivation of a novel neuropeptide Y/peptide YY receptor gene in primate species. | Matsumoto, M., et al. 1996. J Biol Chem. 271: 27217-20. PMID: 8910290
- Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation. | Herzog, H., et al. 1997. Genomics. 41: 315-9. PMID: 9169127
- Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY. | Lutz, CM., et al. 1997. Genomics. 46: 287-90. PMID: 9417917
- Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14. | Darby, K., et al. 1997. Genomics. 46: 513-5. PMID: 9441761
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NPY5-R Antibody (H-4) | sc-137167 | 200 µg/ml | $322.00 | |||
NPY5-R Antibody (H-4): m-IgGκ BP-HRP Bundle | sc-521441 | 200 µg Ab, 40 µg BP | $348.00 | |||
NPY5-R Antibody (H-4): m-IgG2b BP-HRP Bundle | sc-548901 | 200 µg Ab; 10 µg BP | $361.00 | |||
NPY5-R Antibody (H-4) AC | sc-137167 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NPY5-R Antibody (H-4) HRP | sc-137167 HRP | 200 µg/ml | $322.00 | |||
NPY5-R Antibody (H-4) FITC | sc-137167 FITC | 200 µg/ml | $336.00 | |||
NPY5-R Antibody (H-4) PE | sc-137167 PE | 200 µg/ml | $349.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 488 | sc-137167 AF488 | 200 µg/ml | $364.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 546 | sc-137167 AF546 | 200 µg/ml | $364.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 594 | sc-137167 AF594 | 200 µg/ml | $364.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 647 | sc-137167 AF647 | 200 µg/ml | $364.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 680 | sc-137167 AF680 | 200 µg/ml | $364.00 | |||
NPY5-R Antibody (H-4) Alexa Fluor® 790 | sc-137167 AF790 | 200 µg/ml | $364.00 | |||
NPY5-R (H-4) Neutralizing Peptide | sc-137167 P | 100 µg/0.5 ml | $69.00 |