NNT Antibody (G-8): sc-390215
- NNT Antibody (G-8) is a mouse monoclonal IgG2b κ, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 787-1086 mapping at the C-terminus of NNT of human origin
- recommended for detection of NNT of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine, bovine and porcine
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NNT Antibody (G-8) for WB and IHC(P) applications. These reagents are now offered in bundles with NNT Antibody (G-8) (see ordering information below).
QUICK LINKS
SEE ALSO...
NNT Antibody (G-8) is a mouse monoclonal IgG2b antibody that detects NNT in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). NNT, or Nicotinamide nucleotide transhydrogenase, is a crucial 1086 amino acid multi-pass mitochondrial inner membrane protein that plays a vital role in cellular respiration by facilitating the transfer of a hydride ion from NADH to NADP+. This process is essential for maintaining the proton gradient across the inner mitochondrial membrane, which is harnessed by NNT to function as a proton pump. The high concentrations of NADPH produced by NNT are critical for free radical detoxification and various biosynthetic pathways, underscoring NNT′s importance in cellular metabolism and overall cellular health. Anti-NNT antibody (G-8) serves as an invaluable tool for researchers studying mitochondrial function and the metabolic processes that rely on NADPH, providing insights into the mechanisms of energy production and the potential implications in metabolic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NNT Antibody (G-8) | sc-390215 | 200 µg/ml | $322.00 | |||
NNT Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-538070 | 200 µg Ab; 10 µg BP | $361.00 | |||
NNT Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-535602 | 200 µg Ab; 40 µg BP | $361.00 | |||
NNT Antibody (G-8): m-IgG2b BP-HRP Bundle | sc-549916 | 200 µg Ab; 10 µg BP | $361.00 |