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NKp30 Antibody (CLH3) is a mouse monoclonal IgG1 antibody that detects NKp30 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). NKp30 is a critical component of the immune response, particularly in the activation of natural killer (NK) cells, which play a vital role in the body′s defense against tumors and virally infected cells. NKp30 protein is located on the surface of NK cells and is essential for mediating cytotoxicity against target cells, as NKp30 collaborates with other receptors like NKp46 and NKp44 to enhance NK cell activation. NKp30′s structure includes a signal peptide, a V-type immunoglobulin-like domain, a hydrophobic transmembrane region, and a cytoplasmic tail, which is crucial for signaling pathways that lead to the destruction of harmful cells. The presence of potential N-linked glycosylation sites within the extracellular region of NKp30 may also influence stability and interaction with ligands, further underscoring the importance of structural integrity in immune responses. Anti-NKp30 antibody (CLH3) is therefore an invaluable tool for researchers studying the mechanisms of immune activation and the role of NK cells in cancer immunology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NKp30 Antibody (CLH3) | sc-33646 | 200 µg/ml | $322.00 | |||
NKp30 Antibody (CLH3): m-IgG Fc BP-HRP Bundle | sc-536766 | 200 µg Ab; 10 µg BP | $361.00 | |||
NKp30 Antibody (CLH3): m-IgGκ BP-HRP Bundle | sc-533930 | 200 µg Ab; 40 µg BP | $361.00 | |||
NKp30 Antibody (CLH3): m-IgG1 BP-HRP Bundle | sc-544809 | 200 µg Ab; 20 µg BP | $361.00 | |||
NKp30 Antibody (CLH3) FITC | sc-33646 FITC | 200 µg/ml | $336.00 | |||
NKp30 Antibody (CLH3) PE | sc-33646 PE | 200 µg/ml | $349.00 |