Date published: 2026-5-5

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NKG2-D Antibody (A-7): sc-515599

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Datasheets
  • NKG2-D Antibody (A-7) is a mouse monoclonal IgM κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 17-37 near the N-terminus of NKG2-D of mouse origin
  • recommended for detection of NKG2-D of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NKG2-D Antibody (A-7). This work is in progress.
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    NKG2-D Antibody (A-7) is a mouse monoclonal IgM antibody that detects NKG2-D protein of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). NKG2-D (A-7) antibody is available in a non-conjugated form, providing flexibility for various experimental needs. NKG2-D plays a crucial role in the immune response, particularly in the activation of natural killer (NK) cells and certain T cell populations, serving as a receptor for the stress-inducible protein MICA, which is often overexpressed in epithelial tumors. The interaction between NKG2-D and MICA is vital for the immune system′s ability to recognize and eliminate transformed cells, making NKG2-D an important target for cancer immunotherapy. NKG2-D expression occurs on NK cells, γδ T cells and CD8+ αβ T cells, highlighting NKG2-D′s significance in both innate and adaptive immunity. NKG2-D′s ability to mediate immune responses against tumor cells underscores NKG2-D′s potential as a biomarker for cancer progression and a target for therapeutic intervention.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    NKG2-D Antibody (A-7)

    sc-515599
    200 µg/ml
    $322.00

    NKG2-D (A-7) Neutralizing Peptide

    sc-515599 P
    100 µg/0.5 ml
    $69.00

    Dear Tech Support, I would like to purchase this antibody supplied in the formulation containing PBS only. Does your company offert offer special formulation service to NKD2D antibody (A-7)? The catalog number for this antibody is sc-515599.

    Asked by: Kaijin
    Thank you for contacting Santa Cruz Biotechnology. To request a formulation please email specialorders@scbt.com.
    Answered by: BlakeJ
    Date published: 2026-03-12

    What application is the blocking peptide sc-515599 P appropriate for?

    Asked by: TinTin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_5, h_11CST
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    Rated 1 out of 5 by from Does not work for FCMThis NKG2-D antibody does not work for flow cytometry
    Date published: 2018-11-01
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    NKG2-D Antibody (A-7) is rated 1.0 out of 5 by 1.
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