NKG2 Antibody (5K31) is a rat monoclonal IgG2a antibody that detects NKG2 in mouse samples through flow cytometry (FCM). NKG2 is a crucial component of the immune system, primarily expressed on natural killer (NK) cells, as well as on certain T cells, where NKG2 plays a significant role in the recognition and elimination of stressed or transformed cells, such as those found in tumors. The NKG2 family includes several isoforms, which can form heterodimers with CD94, enhancing the immune response against malignancies. The interaction between NKG2 and its ligands, such as the stress-inducible protein MICA, is vital for the activation of NK cells, allowing NK cells to target and destroy cells that exhibit abnormal stress signals. This mechanism is particularly important in cancer immunology, as NKG2 helps the immune system identify and eliminate tumor cells that may otherwise evade detection. Anti-NKG2 antibody (5K31) is an essential tool for researchers studying immune responses, cancer biology, and the intricate signaling pathways that govern NK cell activity.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NKG2 Antibody (5K31) | sc-71707 | 200 µg/ml | $316.00 | |||
NKG2 Antibody (5K31) FITC | sc-71707 FITC | 200 µg/ml | $330.00 | |||
NKG2 Antibody (5K31) PE | sc-71707 PE | 200 µg/ml | $343.00 |