Nitrotyrosine Antibody (6D611) is a mouse monoclonal IgG2a antibody that detects nitrotyrosine in non-species reactive samples by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Nitrotyrosine is a critical biomarker for inflammation and nitric oxide (NO) production, formed in the presence of the active metabolite NO. Anti-nitrotyrosine antibody (6D611) recognizes a stable product of multiple pathways, including the formation of peroxynitrite, which can lead to cellular damage. The presence of nitrotyrosine in plasma is increasingly recognized as a valuable indicator of NO-dependent damage in vivo, making nitrotyrosine essential for understanding inflammatory processes. Elevated levels of nitrotyrosine have been associated with several inflammatory diseases, including septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques, and chronic renal failure, highlighting nitrotyrosine′s importance in both diagnostic and therapeutic contexts. Nitrotyrosine monoclonal antibody (6D611) provides researchers with a powerful tool to investigate these conditions and further explore the underlying mechanisms of inflammation and oxidative stress.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nitrotyrosine Antibody (6D611) | sc-71705 | 200 µg/ml | $322.00 |