Neurofibromin Antibody (E-8): sc-398267
- Neurofibromin Antibody (E-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 507-530 within the N-terminus of Neurofibromin of human origin
- recommended for detection of Neurofibromin of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See Neurofibromin (H-12): sc-376886 for Neurofibromin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Neurofibromin Antibody (E-8) for WB applications. These reagents are now offered in bundles with Neurofibromin Antibody (E-8) (see ordering information below).
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SEE ALSO...
Neurofibromin Antibody (E-8) is a mouse monoclonal IgG1 antibody that detects Neurofibromin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Neurofibromin, also known as NF1-GAP-related protein, is a crucial 2,818 amino acid protein encoded by the NF1 gene located on chromosome 17, and plays a significant role in regulating cell growth and differentiation by acting as a GTPase-activating protein for Ras proteins. The interaction between Neurofibromin and Ras helps control cellular signaling pathways that, when dysregulated, can lead to tumorigenesis, making Neurofibromin a key player in neurofibromatosis type 1 and other related disorders. Neurofibromin is consistently expressed across various tissues, including brain, lung, liver, kidney, spleen, muscle, and colon, highlighting its fundamental role in maintaining normal cellular functions. Anti-Neurofibromin antibody (E-8) is an essential tool for researchers investigating the molecular mechanisms underlying neurofibromatosis and related conditions, providing insights into Neurofibromin′s function and interactions within the cell.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Neurofibromin Antibody (E-8) | sc-398267 | 200 µg/ml | $322.00 | |||
Neurofibromin Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-538410 | 200 µg Ab; 10 µg BP | $361.00 | |||
Neurofibromin Antibody (E-8): m-IgGκ BP-HRP Bundle | sc-536019 | 200 µg Ab; 40 µg BP | $361.00 | |||
Neurofibromin Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-545690 | 200 µg Ab; 20 µg BP | $361.00 | |||
Neurofibromin (E-8) Neutralizing Peptide | sc-398267 P | 100 µg/0.5 ml | $69.00 |