
Neu Antibody (0.N.211) is a mouse monoclonal IgG1 antibody that detects Neu in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Neu, also known as ErbB-2 or HER2, is a member of the epidermal growth factor receptor (EGFR) family, which plays a critical role in cell signaling pathways that regulate cell growth, survival, and differentiation. anti-Neu antibody (0.N.211) recognizes protein interactions with other EGFR family members, such as ErbB-3, which enhances signaling cascades leading to increased tumor cell motility and invasion, as well as modulation of cell cycle checkpoints and apoptotic responses. Notably, amplification and overexpression of Neu are observed in 20-30% of breast carcinomas, making Neu a significant biomarker for disease prognosis and a potential target for therapeutic interventions. Neu monoclonal antibody (0.N.211) provides a valuable tool for researchers investigating Neu′s role in cancer biology and therapeutic development, enabling the exploration of protein interactions and functions in various cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ErbB2/HER2 Antibody (0.N.211) | sc-71667 | 200 µg/ml | $322.00 | |||
ErbB2/HER2 Antibody (0.N.211): m-IgG Fc BP-HRP Bundle | sc-537205 | 200 µg Ab; 10 µg BP | $361.00 | |||
ErbB2/HER2 Antibody (0.N.211): m-IgGκ BP-HRP Bundle | sc-534415 | 200 µg Ab; 40 µg BP | $361.00 |