NEIL3 Antibody (C-1): sc-393799
- NEIL3 Antibody (C-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 23-38 near the N-terminus of NEIL3 of mouse origin
- recommended for detection of NEIL3 of mouse origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-393799 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NEIL3 Antibody (C-1) for WB applications. These reagents are now offered in bundles with NEIL3 Antibody (C-1) (see ordering information below).
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NEIL3 Antibody (C-1) is a mouse monoclonal IgG1 antibody that detects NEIL3 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NEIL3, also known as endonuclease VIII-like 3, plays a crucial role in the cellular response to oxidative DNA damage, functioning as a DNA glycosylase that identifies and excises damaged bases, thereby facilitating the repair process. NEIL3 is primarily localized in the nucleus, which is significant as NEIL3 allows for direct repair of DNA within the site of damage, thus maintaining genomic integrity. NEIL3 is expressed predominantly in thymus and testis tissues, suggesting a specialized function in these areas, possibly related to the high rates of cell division and differentiation occurring in these tissues. NEIL3 consists of 605 amino acids and features both an FPG-type zinc finger and a RanBP2-type zinc finger, which are important for structural stability and functional interactions. The presence of these zinc fingers may enhance NEIL3′s ability to bind to DNA and recognize damaged sites, underscoring NEIL3′s importance in maintaining cellular health and preventing mutations that could lead to diseases such as cancer. Anti-NEIL3 antibody (C-1) is an essential tool for researchers studying DNA repair mechanisms and the implications of oxidative stress in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NEIL3 Antibody (C-1) | sc-393799 | 200 µg/ml | $322.00 | |||
NEIL3 Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-538312 | 200 µg Ab; 10 µg BP | $361.00 | |||
NEIL3 Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-535894 | 200 µg Ab; 40 µg BP | $361.00 | |||
NEIL3 Antibody (C-1): m-IgG1 BP-HRP Bundle | sc-545635 | 200 µg Ab; 20 µg BP | $361.00 | |||
NEIL3 (C-1) Neutralizing Peptide | sc-393799 P | 100 µg/0.5 ml | $69.00 | |||
NEIL3 Antibody (C-1) X | sc-393799 X | 200 µg/0.1 ml | $322.00 |